Project description:Woodchucks that were infected with WHC virus developed HCCs. HCCs and surrounding tissues were removed and RNA was extracted from microarray study. Human, rat and mouse arrays were used due to the lack of a woodchuck array. Same procedures and parameters were used to conduct this experiment. Experiment Overall Design: 3 woodchucks with HCCs were used. HCCs and their surrouding normal tissues were harvested. These 3 pairs of tissues were cross-species hybridized into a human, rat and mouse chip under same conditions. Data analysis were performed to compare the results.
Project description:Woodchucks that were infected with WHC virus developed HCCs. HCCs and surrounding tissues were removed and RNA was extracted from microarray study. Human, rat and mouse arrays were used due to the lack of a woodchuck array. Same procedures and parameters were used to conduct this experiment. Keywords: comparative study
Project description:Gene expression profiling by RNAseq of lung, thymus, heart, pancreas, kidney, spleen and liver tissues from woodchuck as a preclinical animal model for chronic hepatitis B
Project description:Intrahepatic transcriptional signature associated with response to interferon-a treatment in the woodchuck model of chronic hepatitis B
Project description:Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B
Project description:Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Spleen gene expression in uninfected, resolved and chronically infected woodchucks
Project description:Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks
Project description:Transcriptomic analysis of the woodchuck model of chronic hepatitis B: Kidney gene expression in uninfected, resolved and chronically infected woodchucks
