Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: HSV1 gene drive viruses

PROVIDER: PRJNA1077879 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28034040_1.fastq.gz	Fastqsanger.gz
	SRR28034040_2.fastq.gz	Fastqsanger.gz
	SRR28034041_1.fastq.gz	Fastqsanger.gz
	SRR28034041_2.fastq.gz	Fastqsanger.gz
	SRR28034042_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Gene expression profiling of Î³34.5 deleted HSV1 infected Mouse Embryonic Fibroblasts

Project description:Gene expression analysis of wild type and STING knock-out Mouse Embryonic Fibroblasts (MEFs) infected with Î³34.5 deleted HSV1. Genes whose expression that are affected by HSV1 in a STING dependent manner will be identified and signaling pathways regulated by STING will be elucidated. Primary MEFs were mock treated or infected with Î³34.5 deleted HSV1 at M.O.I. 1. Total RNA was extracted 3 hours post infection for array analysis.

2013-01-15 | E-GEOD-43479 | biostudies-arrayexpress

Gene expression profiling of γ34.5 deleted HSV1 infected Mouse Embryonic Fibroblasts

Project description:Gene expression analysis of wild type and STING knock-out Mouse Embryonic Fibroblasts (MEFs) infected with γ34.5 deleted HSV1. Genes whose expression that are affected by HSV1 in a STING dependent manner will be identified and signaling pathways regulated by STING will be elucidated.

2013-01-15 | GSE43479 | GEO

scRNAseq of mock, HSV-1 or HSV-2 infected C57BL/6 Vaginal tissue at 5 days post infection

Project description:Purpose: To compare single cell transcriptional profiling (scRNAseq) of different murine genital herpes infection models with HSV1-McKrae and HSV2-186. Method: DMPA-treated WT C57BL/6 mice were infected with HSV1-McKrae, HSV2-186 or PBS intravaginally. Vaginal tissues were harvested at 5 days post infection, live cells were sorted, a minimum of 16,000 cells were used for scRNAseq. Results: By tSNE visualization of 21,633 cells across all samples, 17 distinct clusters were resolved. We found significantly increased levels of Interferons-Stimulated-Genes (ISGs) in the neutrophils potentially contributing to disease onset and progression in HSV2 genital infections. Conclusion: Our study is the first comparison between the transcriptional signature of two genital herpes model- namely HSV1 and HSV2. Generated by scRNAseq, this study would provide researchers with gene candidates associated with the disease progression and inflammation induced by genital infections with HSV1 and HSV2.

2020-12-31 | GSE161336 | GEO

Effect of HSV1 and hAdV8 infection in human conjunctiva air-liquid interface cultures

Project description:We sought to identify the effect of HSV1 or hAdV8 infection in human conjunctival epithelium.

2024-01-11 | GSE205925 | GEO

Relative accessability of HSV1 genomic DNA compared with its host cell (ATAC-seq)

Project description:To compare the relative accessability of HSV1 DNA compared with its host DNA, we performed ATAC-seq analysis.

2018-07-19 | GSE117335 | GEO

mRNA-Sequencing data of herpes simplex virus type 1 (HSV1)-infected primary mouse microglia

Project description:We report mRNA-Sequencing analysis of primary mouse microglia infected with HSV1 and/or treated with ALT001, which is mitophagy inducing drug

2024-12-31 | GSE278015 | GEO

Gender and prior exposure shape innate immune responses to a replication-defective herpes virus vaccine

Project description:Here we integrate immune profiling and computational approaches to study responses to a replication-defective herpes simplex virus (HSV) 2 vaccine, in men and women either naive or previously exposed to HSV. Subjects were recipients of a herpes simplex virus (HSV) 2 vaccine in a phase 1 clinical trial where comparisons could be made between three groups of human volunteers based on their HSV serostatus prior to vaccination: HSV1-/HSV2- , HSV1+/HSV2-, or HSV1±/HSV2+ Peripheral blood transcriptomics and cell population frequencies showed the greatest changes on day 1 after vaccination. Prior exposure status and gender were independently associated with responses, but the magnitude of innate responses including type I interferon signatures and TLR7 were greatest in HSV naive women. In contrast, subjects previously infected with HSV had more prominent interferon-I responses. Thus, prior exposure and gender interact to shape innate responses that may also impact adaptive immune phenotypes, such as the neutralizing antibody response which was also faster in HSV naive women than men.

2023-01-04 | GSE185341 | GEO

Project description:Transcipt Discoveries of HSV1

| PRJNA381128 | ENA

Novel UL23 and UL30 substitutions in HSV1 and HSV2 viruses related to polymorphism or drug resistance

Project description:Novel UL23 and UL30 substitutions in HSV1 and HSV2 viruses related to polymorphism or drug resistance

| PRJEB64252 | ENA

HSV1 ICP0 associated ubiquitination modulation in N2A neuron cells

Project description:Proteome-wide survey of ubiquitination modulation in N2A neuron cells in response to HSV1 ICP0 transfection and HSV1 infection

2021-01-17 | PXD019782 |

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data