Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of intestinal tissue from mice with and without Eif3h and Apc deficiency.

ABSTRACT: Transcriptional profiling of intestinal tissue from mice with and without Eif3h and Apc deficiency.

PROVIDER: PRJNA1078723 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28027220_1.fastq.gz	Fastqsanger.gz
	SRR28027220_2.fastq.gz	Fastqsanger.gz
	SRR28027221_1.fastq.gz	Fastqsanger.gz
	SRR28027221_2.fastq.gz	Fastqsanger.gz
	SRR28027222_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Transcriptional profiling of intestinal tissue from mice with and without Eif3h and Apc deficiency.

Project description:A profile of gene expression differences in mouse small intestine with and without short term induction of Apc and Eif3h deficiency.

2024-02-26 | GSE256223 | GEO

Transcriptional profiling of regional intestinal tissue from mice with and without Apc deficiency

Project description:Transcriptional profiling of regional intestinal tissue from mice with and without Apc deficiency

| PRJNA957731 | ENA

Transcriptional profiling of intestinal tissue from mice with and without Eif3h deficiency and Kras G12D mutation.

Project description:A profile of gene expression differences in mouse small intestine with and without short term induction of Kras G12D mutation and Eif3h deficiency.

2024-01-21 | GSE253396 | GEO

Impact of beta-arrestin-2 deficiency on intestinal tumorigenesis in Apc-mutated mice

Project description:This SuperSeries is composed of the following subset Series: GSE24575: Beta-arrestin-2 deficiency effect on intestinal tumorigenesis in Apc-mutated mice GSE24576: Gene expression analysis of tumors from ApcD14/+ mice Refer to individual Series

2012-01-20 | E-GEOD-24577 | biostudies-arrayexpress

Transcriptional profiling of short term intestinal tissue in mice with Apc and Kras mutations

Project description:Murine small intestinal tissue following Apc mutation, with or without Kras mutation under the control of VilCreER.

2022-06-30 | GSE197316 | GEO

Transcriptional profiling of intestinal tissue from mice with and without Eif3h deficiency and Kras G12D mutation.

Project description:Transcriptional profiling of intestinal tissue from mice with and without Eif3h deficiency and Kras G12D mutation.

| PRJNA1065455 | ENA

Transcriptional profiling of regional intestinal tissue from mice with and without Apc deficiency

Project description:A profile of gene expression differences along the length of the mouse intestine, in the presence and absence of functional Apc.

2023-04-28 | GSE230144 | GEO

Transcriptional profiling of multiple tissues from mice with and without Apc deficiency

Project description:The effect of whole body Apc deficiency on multiple mouse tissues was examined with RNAseq.

2023-04-28 | GSE230110 | GEO

beta-arrestin-2 deficiency effect on intestinal tumorigenesis in Apc-mutated mice

Project description:Amoung their pleiotropic functions, a role was recently assigned for b-arrestin scaffold proteins in tumor growth, angiogenesis and invasion. In order to elucidate the roles of b-arrestins in tumour developement in intestinal epithelium initiated by Apc mutation, we determined the effects of b-arrestin gene deletion on intestinal polypolis using ApcD14/+ mice, a relevant mouse model of human intestinal tumorigenesis.Here we show that unlike b-arrestin1, absence of b-arrestin2 dramatically decreased the number of spontaneously developping intestinal tumors in ApcD14/+ mice.The size of residual tumors was similarto that of controls, suggesting that their growth is b-arrestin2-independent. This result demonstrated a role for b-arrestin2 in the early development of a tumor subset. Gene expression profils analysis of ApcD14/+:Arrb2+/+ and ApcD14/+:Arrb2-/- tumors showed two distinct clusters among ApcD14/+:Arrb2+/+ tumors and one of them was statistically more correlated to ApcD14/+:Arrb2-/- tumors than to the other ApcD14/+:Arrb2+/+ cluster, eventhough a number of genes saw their expression affected in ApcD14/+:Arrb2-/- tumors only. Altogether, our data unravel an unexpected early diversity among intestinal tumors and a crucial role for b-arrestin2 in early tumor development in Apc-mutated mice. 16 tumors from ApcD14/+:Arrb2+/+ mice and 13 tumors from ApcD14/+:Arrb2-/- mice

2012-01-20 | E-GEOD-24575 | biostudies-arrayexpress

Transcriptional profiling of mouse intestinal tissue, with or without antibiotic or sulindac treatment

Project description:Loss of APC or activation of Braf V600E mutation in combination with Alk5 loss in the intestinal epithelium under the control of VilCreER, with or without antibiotic/sulindac treatment

2021-04-01 | GSE168478 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data