Adhesive metagenome
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1083508 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:We utilize bulk RNA-seq to profile the mRNA expression in day 3 and day 14 post-implantation of SD rat abdminal wall treated with adhesive or non-adhesive implants
2023-06-01 | GSE198219 | GEO
Project description:RNA-sequencing analysis of SD rat abdominal wall treated with adhesive or non-adhesive implant
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Project description:To investigate the effect of Cell-Adhesive Nanofibril on the hepatic differentiation process of 3D iPSC spheroids, we established hepatic organoids that underwent a stepwise hepatic differentiation process with or without Cell-Adhesive Nanofibril.
2023-07-17 | GSE237137 | GEO
Project description:We compared genes from tissue of patients with adhesive capsulitis (AC) with those having surgery for shoulder instability to determine potential biomarkers specific to AC through transcriptomic analysis. Our results presented increased expression of PDGFB, COL18A1 and MMP9 in patients with AC, while TNFA expression was reduced.
2019-11-21 | GSE140731 | GEO
Project description:Throughout all kingdoms of life, a large number of adhesive biomolecules have evolved to allow organisms to adhere to surfaces underwater. Proteins play an important role in the adhesion of numerous marine invertebrates (e.g. mussels, sea stars, sea urchins) whereas much less is known about the biological adhesives from marine plants, including the diatoms. Diatoms are unicellular microalgae that together with bacteria dominate marine biofilms in sunlit habitats. In this study we present the first proteomics analyses of the diatom adhesive material isolated from the tenacious fouling species Amphora coffeaeformis. We identified 21 proteins, of which 13 are diatom specific. Ten of these proteins share a conserved C-terminal domain, termed GDPH domain, which is widespread yet not ubiquitously present in all diatom classes. Immunofluorescence localization of a GDPH domain bearing protein (Ac629) as well as two other proteins identified in this study (Ac1442, Ac9617) demonstrated that these are components of the adhesive trails that are secreted by cells that glide on surfaces.
2021-09-08 | PXD013773 | Pride
Project description:Transcriptomic analysis of adhesive capsulitis of the shoulder
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Project description:Barnacles interest the scientific community for multiple reasons: their unique evolutionary trajectory, vast diversity, and economic impact as a harvested food source and also as one of the most prolific macroscopic hard biofouling organisms. A common, yet novel, trait among barnacles is adhesion, which has enabled a sessile adult existence and global colonization of the oceans. Barnacle adhesive is primarily composed of proteins, but knowledge of how the adhesive proteome varies across the tree of life is unknown due to a lack of genomic information. Here, we supplement previous mass spectrometry analyses of barnacle adhesive with recently sequenced genomes to compare the adhesive proteomes of Pollicipes pollicipes (Pedunculata) and Amphibalanus amphitrite (Sessilia). Although both species contain the same broad protein categories, we detail differences that exist between these species. The barnacle-unique cement proteins show the greatest difference between species, although these differences are diminished when amino acid composition and glycosylation potential are considered. By performing an in-depth comparison of the adhesive proteomes of these distantly related barnacle species, we show their similarities and provide a roadmap for future studies examining sequence specific differences to identify the proteins responsible for functional differences across the barnacle tree of life.
2022-02-17 | PXD026105 | Pride
Project description:Interventions: Others : Comparison of postoperative outcome between conventional skin stapling and tissue adhesive (2-octyl cyanoacrylate) for skin closure in colorectal cancer
Primary outcome(s): comparison of postoperative outcome between conventional skin stapling and tissue adhesive for skin closure in colorectal cancer
Primary Purpose : Treatment, Intervention Model : Parallel, Blinding/Masking : , Blinding Target : , Allocation : RCT
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Project description:The discovery of the natural adhesion phenomena and mechanisms has advanced the information and development of a new generation of tissue adhesives in recent decades. In this study, we developed a natural biological adhesive from snail mucus consisting of a positively charged protein network and a polyanionic glycosaminoglycan network. The malleable bulk adhesive matrix could adhere to wet tissue through multiple interactions. The biomaterial exhibited excellent hemostatic and tissue adhesion properties in vitro and in vivo, and was also effective in accelerating the healing of full-thickness skin wounds in both normal and diabetic rats. The natural biomaterial effectively promoted the polarization of macrophages toward the anti-inflammatory M2 phenotype, alleviated inflammation in chronic wounds, and significantly improved epithelial regeneration and angiogenesis. Its abundant heparin-like glycosaminoglycan component was indispensable. These findings provide theoretical and material insights into bio-inspired tissue adhesives and bioengineered scaffold designs.
2022-11-27 | GSE206113 | GEO
Project description:The base of the barnacle Amphibalanus amphitrite has a layer of protein and cuticle that adheres the barnacle to the surface. The proteins in the adhesive have been characterized, but it is unknown whether the adhesive proteins are associated with the cuticle. To address this possibility, we examined the proteins associated with the molt (exuviae) from the main body, which is also composed of cuticle.
2021-09-08 | PXD013036 | Pride