Project description:Single cell genome-wide gene expression profiling of human embryonic stem cells (hESCs) undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated towards neuronal cells for 13 days, and sampled for downstream analysis at day 0, 6, 10 and 13 . Cells exposed to 50, 100, 200 and 400 nM citalopram from Day 1 were charachterised at Day 6, 10 and 13.
Project description:Genome-wide gene expression profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a novel protocol, and day 0, 7, 13 and 20 were charachterized.
Project description:Genome-wide gene expression profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a novel protocol, and day 0, 7, 13 and 20 were charachterized.
Project description:Genome-wide gene expression profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a novel protocol, and day 0, 7, 13 and 20 were charachterized.
Project description:Genome wide DNA methylation profiling of human embryonic stem cells of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated towards neuronal cells for 13 days, and sampled for downstream analysis at day 0, 6, 10 and 13 . Cells exposed to 50, 100, 200 and 400 nM citalopram from Day 1 were charachterised at Day 6, 10 and 13. The Illumina Infinium MethylationEPIC_v-1-0_B3 was used to obtain DNA methylation profiles accross approximately 850k CpGs in differentiating cells.
Project description:Single-cell RNA-seq of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a novel protocol, and day 0, 7, 13 and 20 were charachterized. Cells exposed to 100 or 200 μM paracetamol from Day 1 were charachterised at Day 7 and Day 20.
Project description:Genome-wide chromatin opening profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a neuronal protocol, and day 20 were charachterized. Cells exposed to 100 or 200 μM paracetamol from Day 1.