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Nab-paclitaxel induces DNA damage and inhibits M2 polarization of macrophages to achieve radiosensitization of cholangiocarcinoma cells.

ABSTRACT: Nab-paclitaxel induces DNA damage and inhibits M2 polarization of macrophages to achieve radiosensitization of cholangiocarcinoma cells.

PROVIDER: PRJNA1093109 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR28492302_1.fastq.gz	Fastqsanger.gz
	SRR28492302_2.fastq.gz	Fastqsanger.gz
	SRR28492303_1.fastq.gz	Fastqsanger.gz
	SRR28492303_2.fastq.gz	Fastqsanger.gz
	SRR28492304_1.fastq.gz	Fastqsanger.gz

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Nab-paclitaxel induces DNA damage and inhibits M2 polarization of macrophages to achieve radiosensitization of cholangiocarcinoma cells.

Project description:Through transcriptome sequencing, it was determined that AMPK is a key pathway involved in the radiosensitization effect of nab-paclitaxel, and its sensitization effect may be attributed to ZMAT3 and NF- κB signaling pathway is closely related.

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c-Myc drives nab-paclitaxel resistance in pancreatic cancer

Project description:c-Myc drives nab-paclitaxel resistance in pancreatic cancer

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