Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The master transcription factor of the Plasmodium merozoite formation. [RNA-Seq]

ABSTRACT: The master transcription factor of the Plasmodium merozoite formation. [RNA-Seq]

PROVIDER: PRJNA1107473 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

The master transcription factor of the Plasmodium merozoite formation. [DIP-seq]

Project description:The master transcription factor of the Plasmodium merozoite formation. [DIP-seq]

| PRJNA1108633 | ENA

The master transcription factor of the Plasmodium merozoite formation. [ChIP-Seq]

Project description:The master transcription factor of the Plasmodium merozoite formation. [ChIP-Seq]

| PRJNA1107471 | ENA

The master transcription factor of the Plasmodium merozoite formation. [RNA-Seq]

Project description:Plasmodium berghei transcriptomes of pbsip2cKO, a parasite line in which pbsip2 is disrupted by DiCre-mediated recombination in the presence of rapamycin, were analyzed at the schizont stage.

2024-11-01 | GSE266503 | GEO

The master transcription factor of the Plasmodium merozoite formation. [ChIP-Seq]

Project description:To investigate the genome-wide binding sites of PbSIP2 in Plasmodium berghei, the chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) analyses were performed. Parasites expressing GFP-fused PbSIP2 (PbSIP2::GFP) in cultures were harvested at 24 h post infection and subjected to ChIP-seq experiments using anti-GFP antibody. Binding sites of PbSIP2 were determined from the sequence data.

2024-11-01 | GSE266502 | GEO

DNA selection by the master transcription factor PU.1

Project description:DNA selection by the master transcription factor PU.1

| PRJNA870593 | ENA

A general transcription co-factor, Smad3, potentiates master transcription factor mediated cell identity conversions

Project description:A general transcription co-factor, Smad3, potentiates master transcription factor mediated cell identity conversions

| PRJNA336438 | ENA

The master transcription factor of the Plasmodium merozoite formation. [DIP-seq]

Project description:To investigate the DNA-binding property of two tandem AP2 domains of PbSIP2, DNA immunoprecipitation followed by high-throughput sequencing (DIP-seq) analysis were performed. Recombinant AP2 domains fused with maltose-binding protein (MBP) were mixed with the P. berghei genomic DNA fragmented via sonication, and protein-DNA complex was harvested using amylose resin. The obtained DNA fragments were sequenced via the next generation sequencing.

2024-11-01 | GSE266869 | GEO

Mapping of the master transcription factor MITF in prostate cancer

Project description:Mapping of the master transcription factor MITF in prostate cancer

| PRJNA996973 | ENA

Profiling γ-irradiated invasive Plasmodium falciparum merozoites using a systems biology approach

Project description:Plasmodium falciparum malaria severely impacts human health. In order to broaden our understanding of merozoite invasion of erythrocytes which is responsible for clinical disease, a P. falciparum γ-irradiated "long-lived merozoite" (LLM) line was investigated. Cell-sieve purified LLM invaded human erythrocytes with an improved efficiency of 10- to 300-fold greater than wild-type (WT) parasites. A comparison of their genomes identified limited changes in the open reading frame of LLM; while only marginal differences were observed in the transcriptomes. Analysis of their proteomes by quantitative mass-spectrometry identified 446 out of 981 proteins of known or unknown function with a significant change in protein abundance (ANOVA p < 0.05). Furthermore, the relative molar concentration of nearly 1100 merozoite proteins was established. Unfortunately, a specific change being responsible for the LLM phenotype was not identified. However, immunoblot analyses of LLM lysates showed proteolytic processing of some proteins of the MSP1 complex and AMA1 were delayed, suggesting that this delayed proteolysis positively impacted merozoite viability and subsequent invasion.

2018-02-14 | GSE81818 | GEO

Prrx1 is a Master Transcription Factor of myofibroblastic Cancer-Associated Fibroblasts

Project description:Prrx1 is a Master Transcription Factor of myofibroblastic Cancer-Associated Fibroblasts

| PRJNA717759 | ENA