Project description:To investigate the effects of DB2115 (PU.1 binding-site inhibitor/redistributor) upon PU.1 genomic localization, the transcriptome and chromatin accessibility.
Project description:This study aims to investigate the effects of PU.1 binding-site inhibitors/redistributors (DB2115, DB2373, DB2750, DB2826) upon the genomic occupancy of PU.1 and to understand DB2115-binding site preference amongst the PU.1 cistrome.
Project description:To investigate the effects of DB2115 (PU.1 binding-site inhibitor/redistributor) upon PU.1 genomic localization, the transcriptome and chromatin accessibility.
Project description:This study aims to investigate the effects of PU.1 binding-site inhibitors/redistributors (DB2115, DB2373, DB2750, DB2826) upon the genomic occupancy of PU.1 and to understand DB2115-binding site preference amongst the PU.1 cistrome.