Project description:The DNA content of bacteriophages from Bartonella grahamii was investigated by hybridization against cellular DNA from the same organism. Phage particles were isolated from plate grown bacteria as well as from different growth phases during culture in liquid medium.
Project description:We transplanted Klebsiella and Lactobacillus to germ free C57/B6J mice. All of the recipients mice were male. Here we report the intestine mRNA profiles of recipients mice with Klebsiella and Lactobacillus.
Project description:The increasing antibiotic resistance of Klebsiella pneumoniae poses a serious threat to global public health. To investigate the antibiotic resistance mechanism of Klebsiella pneumonia, we performed gene expression profiling analysis using RNA-seq data for clinical isolates of Klebsiella pneumonia, KPN16 and ATCC13883. Our results showed that mutant strain KPN16 is likely to act against the antibiotics through increased increased butanoate metabolism and lipopolysaccharide biosynthesis, and decreased transmembrane transport activity.
Project description:http://www.sanger.ac.uk/resources/downloads/bacteria/klebsiella-pneumoniae.htmlThese data are part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
2014-08-08 | E-ERAD-246 | biostudies-arrayexpress
Project description:Isolation, Characterization and Evaluation of Lytic Bacteriophages from Wastewater against MDR Klebsiella Spp