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Effect of melatonin during LPS-induced inflammation on RAW 264.7 cells

ABSTRACT: Effect of melatonin during LPS-induced inflammation on RAW 264.7 cells

PROVIDER: PRJNA1121248 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR29320000_1.fastq.gz	Fastqsanger.gz
	SRR29320000_2.fastq.gz	Fastqsanger.gz
	SRR29320001_1.fastq.gz	Fastqsanger.gz
	SRR29320001_2.fastq.gz	Fastqsanger.gz
	SRR29320002_1.fastq.gz	Fastqsanger.gz

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Effect of melatonin during LPS-induced inflammation on RAW 264.7 cells

Project description:Melatonin is a powerful anti-inflammatory agent and antioxidant. To explore specific anti-inflammatory mechanisms, LPS was used to intervene in RAW 264.7 cells to construct an inflammation model. Then, cells were pretreated with melatonin at concentrations of 10-3M to 10-7M, respectively. The above cells were subjected to DRUG-seq sequencing to explore the specific mechanism of melatonin anti-inflammation.

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Gene expression of RAW 264.7 cells treated with LPS, ISO, PGE2, LPS PLUS ISO, and LPS PLUS PGE2

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Effect of LPS and LPS-binding protein treatment on RAW 264.4 cells

Project description:All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RAW 264.4 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. This SuperSeries is composed of the following subset Series: GSE1099: Effect of LPS and LPS-binding protein treatment for 1 hour on RAW 264.4 cells GSE1100: Effect of LPS and LPS-binding protein treatment for 2 hours on RAW 264.4 cells GSE1101: Effect of LPS and LPS-binding protein treatment for 4 hours on RAW 264.4 cells GSE1102: Effect of LPS and LPS-binding protein treatment for 8 hours on RAW 264.4 cells GSE1103: Effect of LPS and LPS-binding protein treatment for 16 hours on RAW 264.4 cells GSE1104: Effect of LPS and LPS-binding protein treatment for 48 hours on RAW 264.4 cells Refer to individual Series

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