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Differential gene expression in SK-MEL-5 and MALME-3M cell lines following IFN-γ treatment

ABSTRACT: Differential gene expression in SK-MEL-5 and MALME-3M cell lines following IFN-γ treatment

PROVIDER: PRJNA1121942 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR29339455_1.fastq.gz	Fastqsanger.gz
	SRR29339455_2.fastq.gz	Fastqsanger.gz
	SRR29339456_1.fastq.gz	Fastqsanger.gz
	SRR29339456_2.fastq.gz	Fastqsanger.gz
	SRR29339457_1.fastq.gz	Fastqsanger.gz

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Differential gene expression in SK-MEL-5 and MALME-3M cell lines following IFN-γ treatment

Project description:This study explores the effects of IFN-γ treatment on gene expression in two melanoma cell lines, SK-MEL-5 and MALME-3M. Using RNA sequencing, we aimed to identify differentially expressed lncRNA genes that respond to IFN-gamma, which could illuminate pathways involved in immune response modulation in melanoma cells.

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Project description:MYC-inducible SK-MEL-28 cells with or without MYC-induction were analyzed

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Project description:HiC experiment done on SK-MEL-5 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

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Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines

Project description:We recently reported that single-cell derived isogenic subclones of SKMEL5 cells have differential initial sensitivity to BRAF-inhibitors. In order to probe differences among these subclones, we selected three subclones with unique drug responses: progressing (SK-MEL-5 SC10), stationary (SK-MEL-5 SC07), and regressing (SK-MEL-5 SC01) and performed RNASeq. This study examines differentially expressed genes (DEGs) among the subclones to identify the molecular basis for initial differences in drug sensitivity.

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RAMPAGE from SK-MEL-5 (ENCSR054RIR)

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MKK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 cells.

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RAMPAGE from SK-MEL-5 (ENCSR007RIV)

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2016-11-08 | GSE87952 | GEO

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