Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNAseq of patient-derived colon organoids treated with 3PO for 24h

ABSTRACT: RNAseq of patient-derived colon organoids treated with 3PO for 24h

PROVIDER: PRJNA1125411 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

RNAseq of patient-derived colon organoids treated with 3PO for 24h

Project description:To evaluate 3PO-induced changes on cellular transcriptomes in a more advanced in vitro model, patient-derived organoids (PDOs) of three different patients were treated with 30 ¬µM 3PO for 24h and their RNA was extracted and sequenced. Next, the resulting gene expression data were interpreted by Gene Set Enrichment Analysis (GSEA).

2024-06-26 | GSE270210 | GEO

Bulk RNA-seq of MilliporeSigma SCC300 human iPSC-derived colon organoids compared with undifferentiated human iPSCs and MilliporeSigma SCC321 human patient-derived colon organoids

Project description:Experiment intended to obtain expression profiles of iPSC-derived human colon organoids compared to undifferentiated human iPSCs and a patient-derived colon organoid line

2021-10-25 | E-MTAB-11026 | biostudies-arrayexpress

RNA-seq of BRAF-V600E_mutated and BRAF-V600E_corrected colon cancer organoids

Project description:We aimed to investigate transcriptional changes in human colon cancer organoids with the BRAF-V600E mutation and in human colon cancer organoids in which the BRAF-V600E mutation was corrected by means of CRISPR genome editing. RNAseq was performed at USEQ at the UMC Utrecht (The Netherlands).

2024-02-21 | E-MTAB-13806 | biostudies-arrayexpress

RNA-seq of BRAF-wildtype and BRAF-V600E_knock-in healthy colon organoids

Project description:We aimed to investigate transcriptional changes in human healthy colon organoids where the BRAF-V600E mutation was knocked-in by means of CRISPR genome editing. RNAseq was performed at USEQ at the UMC Utrecht (The Netherlands).

2024-03-08 | E-MTAB-13842 | biostudies-arrayexpress

Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids

Project description:Purpose: The objective of this study is to compare the transcriptome profile of intestinal epithelial organoids cultivated from distal colon tissue of patients with ulcerative colitis vs organoids cultivate from non-matched and otherwise healthy patient colon

2018-07-15 | GSE102746 | GEO

Transcriptome-wide in vitro effects of aspirin on patient-derived normal colon organoids

Project description:Here, we used bulk RNA-seq data derived from healthy colon organoids (un)exposed to aspirin. Through the use of external single cell RNA-seq data, we estimate changes in cell composition. We extend this analysis by controlling for cell composition and performing WGCNA to identify modules of co-expression differentially affected by aspirin treatment in colon organoids.

2021-01-31 | GSE163282 | GEO

Transcriptomic profiling of patient-derived endometrial cancer organoids (Berg HF)

Project description:Patient-derived endometrial cancer organoids. The data was used to compare gene expression profile between organoids, and to explore whether an organoid-derived gene signature could predict disease outcomes in independent patient cohorts.

2021-07-16 | E-MTAB-10664 | biostudies-arrayexpress

Transcriptome-wide in vitro effects of aspirin on patient-derived normal colon organoids

Project description:Transcriptome-wide in vitro effects of aspirin on patient-derived normal colon organoids

| PRJNA685544 | ENA

H3K27 acetylation profiling of intestinal epithelial organoids cultivated from normal and colitic human primary colon mucosal tissue

Project description:We report the results of ChIP-Seq profiling of H3K27 acetylation loci in intestinal epithelial organoids cultivated from primary patient colon tissue

2018-07-15 | GSE103476 | GEO

scGET-seq profile of patient derived organoids

Project description:Two patient-derived organoids from liver metastasis of CRC samples were profiled by scGET-seq to analyze their genomic composition

2021-08-17 | E-MTAB-10219 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data