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Son KD in mouse embryonic stem cells

ABSTRACT: Son KD in mouse embryonic stem cells

PROVIDER: PRJNA1128624 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR29591159_1.fastq.gz	Fastqsanger.gz
	SRR29591159_2.fastq.gz	Fastqsanger.gz
	SRR29591160_1.fastq.gz	Fastqsanger.gz
	SRR29591160_2.fastq.gz	Fastqsanger.gz

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Son KD in mouse embryonic stem cells

Project description:Gene-expression noise can influence cell-fate choices across pathology and physiology. However, a crucial question persists: do regulatory proteins or pathways exist that control noise independently of mean expression levels? Resulting from a previous screen, the protein SON was identified as a potential noise regulator. We perform Son KD and utilize single-cell RNA sequencing (scRNA-seq) to quantify the changes in mean/noise of all transcripts. This dataset corresponds to the aforementioned scRNA-seq experiment upon Son KD.

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Total RNA-seq and long-read RNAseq (Nanopore) upon Son KD in mouse embryonic stem cells

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