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Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation [RNA-seq]

ABSTRACT: Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation [RNA-seq]

PROVIDER: PRJNA1129875 | ENA |

REPOSITORIES: ENA

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Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation

Project description:Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation

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Project description:This SuperSeries is composed of the SubSeries listed below.

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Expression data from wildtype and Tfr1 heart KO mice

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Project description:Tfr1 is important for iron uptake in red blood cells. We deleted Tfr1 in skeletal muscle to determine the role of Tfr1 in iron uptake in skeletal muscle. We used microarrays to identify global gene changes associated with deletion of Tfr1 in skeletal muscle We used skeletal muscle and liver from wild type and Tfr1 skeletal muscle KO mice at postnatal day 5 and postnatal day 9. mRNA was extracted from the tissues, labaled and hibridized to Affymetrics microarrays.

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Nuclear transport surveillance of p53 by nuclear pores in glioblastoma

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