Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1133006 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR29740000_1.fastq.gz | Fastqsanger.gz | |||
| SRR29740000_2.fastq.gz | Fastqsanger.gz | |||
| SRR29740001_1.fastq.gz | Fastqsanger.gz | |||
| SRR29740001_2.fastq.gz | Fastqsanger.gz | |||
| SRR29740002_1.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 5 of 28 |
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Project description:Purpose: To study the alteration of whole transcriptome of Lewis lung carcinoma (LLC) cells after the decreasing of malignant properties of tumor by treatment of tumor-bearing mice with RNase A. Methods: Whole transcriptome profile of Lewis lung carcinoma before and after RNase A treatment were generated by deep sequencing using SOLiD 5.5. The sequence reads were mapped by Bioscope 1.3 software, differential expression was evaluated by Cufflinks v.2.0.1 package. Results: Difference in expression was found for 966 genes. Conclusions: Our study represents the first detailed analysis of alteration of transcriptome of Lewis lung carcinoma after the decrease of malignant prtoperties of the tumor (proliferation and invasion) by RNase A.
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