Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis - Monocyte

ABSTRACT: Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis - Monocyte

PROVIDER: PRJNA1140184 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29993627_1.fastq.gz	Fastqsanger.gz
	SRR29993627_2.fastq.gz	Fastqsanger.gz
	SRR29993628_1.fastq.gz	Fastqsanger.gz
	SRR29993628_2.fastq.gz	Fastqsanger.gz
	SRR29993629_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis - Monocyte

Project description:Obesity and altered lipid metabolism are associated with colorectal cancer (CRC). In this context, the presence of colonic lipid-engulfed macrophages (foam cells, FC) may hinder protective T cell immunity, thus favoring gut carcinogenesis.

2024-07-25 | GSE273106 | GEO

Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis

Project description:Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis

| PRJNA944128 | ENA

Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis

Project description:Obesity and altered lipid metabolism is associated with colorectal cancer (CRC). In this context, the presence of colonic lipid-engulfed macrophages (foam cells, FC) may be involved in hindering protective T cell immunity, thus favoring gut carcinogenesis.

2023-03-19 | GSE227206 | GEO

Platelets favor the outgrowth of established metastases

Project description:Platelets favor the outgrowth of established metastases

| PRJEB73382 | ENA

Spink4 modulates gut microbiota to interfere IgA production

Project description:Spink4 modulates gut microbiota to interfere IgA production Raw sequence reads

| PRJNA1046498 | ENA

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly

Project description:Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly

| PRJNA1092583 | ENA

IL-4 signals interfere with regulatory T cell polarization in vitro by controlling their genome-wide chromatin accessibility

Project description:IL-4 signals interfere with regulatory T cell polarization in vitro by controlling their genome-wide chromatin accessibility

2021-05-12 | GSE152810 | GEO

Virus-induced codon-specific reprogramming to favor viral RNA translation

Project description:How viruses, such as the emerging mosquito-borne Chikungunya virus (CHIKV), express their genomes at high levels despite an enrichment in suboptimal codons remains a puzzling question. By integrating subcellular fractionation and transcriptome-wide analyses of translation in CHIKV-infected human cells, we demonstrate an unanticipated virus-induced reprogramming of the host translation machinery to favor translation of viral RNA over cellular genes featuring optimal codon usage. This reprogramming was specifically apparent at the endoplasmic reticulum (ER), the preferred translation compartment of CHIKV RNA, and it is mediated by the wobble uridine 34 tRNA modification enzyme KIAA1456 whose expression is enhanced upon viral infection. Since KIAA1456 itself is encoded by a CHIKV-like codon usage, infection triggers a positive feed-back loop that ensures efficient virus protein production. Our findings demonstrate an unprecedented interplay of viruses with the host tRNA epitranscriptome to favor viral protein expression.

2022-06-17 | GSE143390 | GEO

Circadian clock, carcinogenesis, chronochemotherapy connections

Project description:Circadian clock, carcinogenesis, chronochemotherapy connections

| PRJNA739695 | ENA

Epigenetic reprogramming in hepatic carcinogenesis

Project description:Epigenetic reprogramming in hepatic carcinogenesis

| PRJNA450821 | ENA