Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomic profiling of adipose tissues across estrous cycles in mice.

ABSTRACT: Transcriptomic profiling of adipose tissues across estrous cycles in mice.

PROVIDER: PRJNA1150573 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptomic profiling of adipose tissues across estrous cycles in mice.

Project description:To investigate the impact of the reproductive cycle on adipose tissue, we analyzed transcriptome profiling across the entire estrous cycle in the adipose tissue of female mice.

2024-09-18 | GSE275383 | GEO

Transcriptome dataset of mouse adipose tissue across estrous cycles.

Project description:Adipose tissue is crucial for energy storage and release, ensuring energy homeostasis within the body. Disturbances in the physiology of adipose tissue have been associated with various health disorders, such as obesity and diabetes. The reproductive cycle represents a fundamental biological pattern in female physiology. Although previous research has highlighted the substantial regulatory influence of ovarian hormones on adipose tissue, our understanding of the comprehensive changes in adipose tissue throughout the reproductive cycle remains limited. In this study, we examined the transcriptomic profile of female mouse-adipose tissue across their complete estrous cycles. The findings provided detailed descriptions of the datasets generated, including information on data collection, processing, and quality control. The study also demonstrated the robustness of these data through various validation steps. These findings serve as crucial resources for investigating the role of estrous cycle rhythmicity in important adipose tissue processes in the future.

| S-EPMC11455834 | biostudies-literature

Comparative transcriptome data of multi tissues in response to different environmental light-dark cycles

Project description:It is well known that host-microbes and immunity interactions are influenced by dietary patterns, as well as daily environmental light-dark (LD) cycles that entrain circadian rhythms in the host. Emerging data has highlighted the importance of diet patterns and timing on the interaction among circadian rhythms, gut microbiome, and immunity, however, their impacts on LD cycles are less reported. Therefore, we aim to study how LD cycles regulate the homeostatic crosstalk between gut microbiome, hypothalamic and hepatic circadian clock oscillations and immunity. We hypothesized that different environmental LD cycles: (1) constant darkness, LD0/24; (2) short light, LD8/16; (3) normal LD cycle, LD12/12; (4) long light, LD16/8; and (5) constant light, LD24/0, may affect immunity and metabolism to varying degrees. Therefore, 240 mice were managed with chow diets (CD) and antibiotics treatments (ABX) under five different LD cycles for 42 days. The liver (LIV), hypothalamus (HYP), inguinal white adipose tissue (iWAT), ileum epithelium (ILE), colon epithelium (COL), jejunum epithelium (JEJ), cecum epithelium (CEC), spleen (SPL), mammary gland (MAG), and thymus gland (THY) tissues were obtained for studying their impacts immunity using RNA-Seq data.

2023-03-10 | GSE226855 | GEO

miRNA expression from mouse adipose tissues

Project description:miRNA expression from mouse adipose tissues

| PRJNA897925 | ENA

Transcriptome analysis of mice adipose tissues

Project description:Transcriptome analysis of mice adipose tissues

| PRJNA494383 | ENA

White adipose tissues: amphiregulin overexpression

Project description:Transcriptional profiling of transgenic mice specifically expressing amphiregulin in white adipose tissues. The objective of this study is to explore gene expression profiles of adipose tissues in response to amphiregulin overexpression.

2017-09-15 | GSE103875 | GEO

The role of somatosensory innervation of adipose tissues

Project description:To investigate the role of somatosensory innervation of adipose tissues, we unilaterally ablate sensory innervation of adipose tissues, and profiled the gene expression in the inguinal adipose tissues 4 weeks after sensory ablation surgery.

2022-07-10 | GSE207664 | GEO

Transcriptome-wide maps of subcutaneous adipose tissues and visceral adipose tissues in cancer-associated cachexia patients

Project description:Transcriptome-wide maps of subcutaneous adipose tissues and visceral adipose tissues in cancer-associated cachexia patients

| PRJNA773957 | ENA

Gene expression profiling of mouse brown and white adipose tissues

Project description:Gene expression profiling of supraclavicular brown, interscapular brown, inguinal white, and epididymal white adipose tissues from C57BL/6 male mice was performed by RNA-sequencing.

2017-09-08 | GSE92844 | GEO

Transcriptomic and lipidomic profiling of subcutaneous and visceral adipose tissues in 15 vertebrates.

Project description:The storage of lipids as energy in adipose tissue (AT) has been conserved over the course of evolution. However, substantial differences in ATs physiological activities were reported among species. Hence, establishing the mechanisms shaping evolutionarily divergence in ATs transcriptomes could provide a deeper understanding of AT regulation and its roles in obesity-related diseases. While previous studies performed anatomical, physiological and morphological comparisons between ATs across different species, little is currently understood at the molecular phenotypic levels. Here, we characterized transcriptional and lipidomic profiles of available subcutaneous and visceral ATs samples across 15 vertebrate species, spanning more than 300 million years of evolution, including placental mammals, birds and reptiles. We provide detailed descriptions of the datasets produced in this study and report gene expression and lipid profiles across samples. We demonstrate these data are robust and reveal the AT transcriptome and lipidome vary greater among species than within the same species. These datasets may serve as a resource for future studies on the functional differences among ATs in vertebrate species.

| S-EPMC10338492 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data