Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mouse gut metagenome

ABSTRACT: Circadian disorganization alters intestinal microbiota

PROVIDER: PRJNA1165214 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR30819800.fastq.gz	Fastqsanger.gz
	SRR30819801.fastq.gz	Fastqsanger.gz
	SRR30819802.fastq.gz	Fastqsanger.gz
	SRR30819803.fastq.gz	Fastqsanger.gz
	SRR30819804.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 41

Similar Datasets

mouse gut metagenome

Project description:Circadian-Induced Changes in Intestinal Microbiota

| PRJNA217690 | ENA

mouse gut metagenome

Project description:Gliadin intake alters intestinal microbiota in mice fed a high-fat diet

| PRJNA293119 | ENA

Relating human gut metagenome and metaproteome

Project description:Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and shotgun metaproteomics. We found a considerable divergence between genetic potential and functional activity of the human healthy gut microbiota, in spite of a quite comparable taxonomic structure revealed by the two approaches. Investigation of inter-individual variability of taxonomic features revealed Bacteroides and Akkermansia as remarkably conserved and variable in abundance within the population, respectively. Firmicutes-driven butyrogenesis (mainly due to Faecalibacterium spp.) was shown to be the functional activity with the higher expression rate and the lower inter-individual variability in the study cohort, highlighting the key importance of the biosynthesis of this microbial by-product for the gut homeostasis. The taxon-specific contribution to functional activities and metabolic tasks was also examined, giving insights into the peculiar role of several gut microbiota members in carbohydrate metabolism (including polysaccharide degradation, glycan transport, glycolysis and short-chain fatty acid production). In conclusion, our results provide useful indications regarding the main functions actively exerted by the gut microbiota members of a healthy human cohort, and support metaproteomics as a valuable approach to investigate the functional role of the gut microbiota in health and disease.

2017-07-19 | PXD005780 | Pride

mouse gut metagenome

Project description:The Circadian Clock Mutation Promotes Intestinal Dysbiosis

| PRJNA1086924 | ENA

mouse gut metagenome

Project description:The Circadian Clock Mutation Promotes Intestinal Dysbiosis (Revised)

| PRJNA1088096 | ENA

The intestinal microbiota regulates body composition through NFIL3 and the circadian clock

Project description:The intestinal microbiota has been identified as an environmental factor that markedly impacts energy storage and body fat accumulation, yet the underlying mechanisms remain unclear. Here we show that the microbiota regulates body composition through the circadian transcription factor NFIL3. Nfil3 transcription oscillates diurnally in intestinal epithelial cells and the amplitude of the circadian oscillation is controlled by the microbiota through type 3 innate lymphoid cells (ILC3), STAT3, and the epithelial cell circadian clock. NFIL3 controls expression of a circadian lipid metabolic program and regulates lipid absorption and export in intestinal epithelial cells. These findings provide mechanistic insight into how the intestinal microbiota regulates body composition and establish NFIL3 as an essential molecular link among the microbiota, the circadian clock, and host metabolism.

2017-09-26 | GSE100339 | GEO

Metagenome sequencing of feces of mouse treated D-galactose or not

Project description:D-galactose orally intake ameliorate DNCB-induced atopic dermatitis by modulating microbiota composition and quorum sensing. The increased abundance of bacteroidetes and decreased abundance of firmicutes was confirmed. By D-galactose treatment, Bacteroides population was increased and prevotella, ruminococcus was decreased which is related to atopic dermatitis.

2022-04-29 | E-MTAB-11632 | biostudies-arrayexpress

mouse gut metagenome

Project description:Mouse intestinal microbiota Targeted Locus (Loci)

| PRJNA209582 | ENA

mouse gut metagenome

Project description:Mice Intestinal Microbiota Raw sequence reads

| PRJNA293504 | ENA

mouse gut metagenome

Project description:Microbiota of intestinal contents of dissected mice

| PRJDB5189 | ENA