Project description:Chromatin openness is a good indicator of non-coding regulatory elements. Here, we generated ATAC-seq of 8 breast cancer cell lines covering different breast cancer subtypes as an overview of the open chromatin landscapes.
Project description:Numerous studies have highlighted the critical role of genetic and epigenetic modifications in the regulation of oxaliplatin resistance, but whether changes involving chromatin structure have not been fully investigated. We have integrated a variety of techniques to explore a comprehensive overview of chromatin changes in oxaliplatin-resistant processes.
Project description:Numerous studies have highlighted the critical role of genetic and epigenetic modifications in the regulation of oxaliplatin resistance, but whether changes involving chromatin structure have not been fully investigated. We have integrated a variety of techniques to explore a comprehensive overview of chromatin changes in oxaliplatin-resistant processes.
