Project description:Lysinibacillus sphaericus produces the mosquito larvicidal binary toxin consisting of BinA and BinB, which are both required for toxicity against Culex and Anopheles larvae. The molecular mechanisms behind Bin toxin-induced damage remain unexplored. We used whole-genome microarray-based transcriptome analysis to better understand how Culex larvae respond to Bin toxin treatment at the molecular level. Our analyses of Culex quinquefasciatus larvae transcriptome changes at 6, 12, and 18 h after Bin toxin treatment revealed a wide range of transcript signatures, including genes linked to the cytoskeleton, metabolism, immunity, and cellular stress, with a greater number of down-regulated genes than up-regulated genes. Bin toxin appears to mainly repress the expression of genes involved in metabolism, the mitochondrial electron transport chain, and the protein transporter of the outer/inner mitochondrial membrane. The induced genes encode proteins linked to mitochondrial-mediated apoptosis and cellular detoxification including autophagic processes and lysosomal compartments.
Project description:A protein pilot dataset detecting Wolbachia proteins from protein extracted from dissected infected Culex pipiens mosquito ovaries. The experiment was based of an iTRAQ experiment comparing infected and uninfected ovarian tissues and has been usefull in characterizing the wPip (Buckeye) ovarian proteome.
Project description:This dataset is in support of a manuscript in preparation by Retallack et al. (2020). Data included here represent mosquito and viral protein sequences identified in a mosquito cell line persistently infected with Culex narnavirus 1.
Project description:The following dataset is a Wolbachia proteome derived from protein extractions of infected ovaries of the mosquito host Culex pipiens.
2016-04-21 | MSV000079672 | MassIVE
Project description:Population genomics in Beauveria spp.
| PRJNA744643 | ENA
Project description:Population genomics of Rhynchosporium spp.
Project description:Culex pipiens (northern house mosquito)
| PRJEB67318 | ENA
Project description:Metagenomic analysis 21 Culex pipiens and Culex torrentium mosquito
| PRJNA644283 | ENA
Project description:Genomic differentiation and intercontinental population structure of mosquito vectors Culex pipiens pipiens and Culex pipiens molestus