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Analysis of gene regulation by the TP63 isoforms deltaNp63alpha and deltaNp63beta

ABSTRACT: Analysis of gene regulation by the TP63 isoforms deltaNp63alpha and deltaNp63beta

PROVIDER: PRJNA1193517 | ENA |

REPOSITORIES: ENA

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Analysis of gene regulation by the TP63 isoforms deltaNp63alpha and deltaNp63beta

Project description:We analyzed the transcriptome changes of the colon carcinoma cell line HCT116 TP53-/- in response to expression of the TP63 isoforms deltaNp63alpha or deltaNp63beta. The goal was to understand how these C-terminal isoforms of p63 might differentially regulate gene expression.

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Analysis of gene regulation by the TP63 isoforms deltaNp63alpha and deltaNp63beta using ChIPseq of p63 and H3K27ac

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Analysis of gene regulation by the TP63 isoforms deltaNp63alpha and deltaNp63beta using ChIPseq of p63 and H3K27ac

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Co-expression analysis reveals gene cluster associated with methylation of enhancers and chromosomal instability under TP63 and TRIM29 regulation.

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Co-expression analysis reveals gene cluster associated with methylation of enhancers and chromosomal instability under TP63 and TRIM29 regulation [methylation]

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