Project description:We collected samples of Pistil, Plain Valve, Plain lip and Plain calyx from the same period and quenched them in liquid nitrogen. Two biological replications were performed in each sample. TMT labeled quantitative proteomics was used to analyze different proteins in different tissues. GO and KEGG were used to analyze the differentially expressed proteins in different tissues, and the key proteins in the important pathway were found
Project description:Typhoid fever is caused by the Gram-negative bacterium Salmonella enterica serovar Typhi. Bulk RNA-sequencing (RNA-seq) data were generated from blood samples obtained from adult human volunteers enrolled in a vaccine trial involving two vaccines against typhoid fever, a plain polysaccharide vaccine, ViPS and a glycoconjugate vaccine, ViTCV. The participants were then challenged with S. Typhi in a controlled human infection model (CHIM).