Project description:We study the changes occurring in the testes of Talpa occidentalis during the breeding cycle. The transcriptomic analysis of active, inactivating and regressed testis show that several molecular pathways that operate in Sertoli cells, involved in the control of spermatogenesis and BTB dynamics, are deregulated in the inactive gonad, and that the immuno privilege of the testes is lost during the non-breeding season.
