Project description:Campylobacter jejuni is a common cause of diarrheal disease worldwide. Human infection typically occurs through the ingestion of contaminated poultry products. We previously demonstrated that an attenuated Escherichia coli live vaccine strain expressing the C. jejuni N-glycan on its surface reduces the Campylobacter load in more than 50% of vaccinated leghorn and broiler birds to undetectable levels (responder birds), whereas the remainder of the animals were still colonized (non-responders). To understand the underlying mechanism, we conducted 3 larger scale vaccination and challenge studies using 135 broiler birds and found a similar responder/non responder effect. The submitted data were used for a genome-wide association study of the chicken responses to glycoconjugate vaccination against Campylobacter jejuni.
2021-11-01 | GSE181619 | GEO
Project description:Genomes of Campylobacter strains isolated from Human cases in Switzerland
| PRJNA1223812 | ENA
Project description:Sequencing of Aspergillus fumigatus strains isolated from wild birds
Project description:Transcriptional profiling of Campylobacter jejuni NCTC 11168 wild type and LuxS01 mutant strains comparing the effects of exogenously added in vitro-produced autoinducer 2 (AI-2) versus a control buffer to both strains.
2009-10-08 | GSE18427 | GEO
Project description:Whole genome sequences of Enterococcus faecalis strains isolated from wild birds
Project description:C. coli is the predominant Campylobacter strain that is found in pigs while C. jejuni if present will be 10- 100 folds less. Natural transformation can occur if there is a coexistence of both the strains in the intestine of pigs. Genome analyses were performed on a C. jejuni strain U101 isolated from the upper intestine and two C. coli strains, C101 and L101 isolated from caecum and lower intestine.
