Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

CEBPB-high dormant tumor cells drive immune evasion [ChIP-Seq]

ABSTRACT: CEBPB-high dormant tumor cells drive immune evasion [ChIP-Seq]

PROVIDER: PRJNA1225950 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

CEBPB-high dormant tumor cells drive immune evasion [RNA-Seq]

Project description:CEBPB-high dormant tumor cells drive immune evasion [RNA-Seq]

| PRJNA1225951 | ENA

CEBPB-high dormant tumor cells drive immune evasion [ChIP-Seq]

Project description:Triple negative breast cancer (TNBC) poorly responds to immune checkpoint blockade (ICB) therapy. Dormant tumor cells are recognized as immunotherapy-resistant reservoirs, potential leading to tumor relapse, highlighting the importance to elucidate the mechanisms underlying immunotherapy resistance. Herein, we demonstrated that dormant tumor cells were resistant to ICB therapy and occupied an immunosuppressive niche with enhanced tumor-associated macrophages (TAMs) and decreased CD8+T cells infiltration in mouse TNBC allografts via a label-retention system. CEBPB was highly expressed in dormant tumor cells and maintained tumor dormancy by transcriptionally activating cell cycle negative regulators like CCNG2 and p27.

2025-02-21 | GSE290039 | GEO

CEBPB-high dormant tumor cells drive immune evasion [RNA-Seq]

2025-02-21 | GSE290038 | GEO

Expression profile of human breast cancer cells with CEBPB overexpression

Project description:CEBPB contributes to the migration of breast cancer cells. We used microarrays to detail the mechanism of CEBPB with downstream targets that drive breast cancer cell migration. CEBPB were overexpressed in MDA-MB231 cell for RNA extraction and hybridization on Agilent microarrays. We sought to obtain the mechanisms of CEBPB with downstream proteins that drive breast cancer cell migration.

2015-03-31 | E-GEOD-67425 | biostudies-arrayexpress

Ovarian cancer mutational processes drive site-specific immune evasion

Project description:Ovarian cancer mutational processes drive site-specific immune evasion

| PRJNA749041 | ENA

Expression profile of human breast cancer cells with CEBPB overexpression

2015-03-31 | GSE67425 | GEO

INTERCELLULAR HIF1alpha REPROGAMS MAMMARY PROGENITORS AND MYELOID IMMUNE EVASION TO DRIVE HIGH-RISK BREAST LESIONS

Project description:INTERCELLULAR HIF1alpha REPROGAMS MAMMARY PROGENITORS AND MYELOID IMMUNE EVASION TO DRIVE HIGH-RISK BREAST LESIONS

| PRJNA938149 | ENA

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Project description:mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

| PRJNA883227 | ENA