Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Caenorhabditis elegans

ABSTRACT: High throughput sequencing of mutants in the WAGO pathway

OTHER RELATED OMICS DATASETS IN: GSE18231

PROVIDER: PRJNA123493 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR030710.fastq.gz	Fastqsanger.gz
	SRR030711.fastq.gz	Fastqsanger.gz
	SRR030712.fastq.gz	Fastqsanger.gz
	SRR030713.fastq.gz	Fastqsanger.gz
	SRR030714.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

Caenorhabditis elegans

Project description:High throughput sequencing of endogenous small RNAs from AGO pathway mutants

| PRJNA123835 | ENA

E-GEOD-48767

Project description:Transcription profiling by high throughput sequencing of Arabidopsis phyA-1 mutants

2019-05-14 | E-GEOD-48767 | ExpressionAtlas

E-GEOD-60387

Project description:Transcription profiling by high throughput sequencing of Arabidopsis lsm4-1 mutants and sad1/lsm5 double mutants

2019-05-14 | E-GEOD-60387 | ExpressionAtlas

E-GEOD-70584

Project description:Transcription profiling by high throughput sequencing of the endodermis of Arabidopsis myb36 mutants

2016-05-03 | E-GEOD-70584 | ExpressionAtlas

E-GEOD-38400

Project description:Transcription profiling by high throughput sequencing of Arabidopsis swi3b/+, nrpe1, and idn2-1 mutants

2016-05-03 | E-GEOD-38400 | ExpressionAtlas

E-MTAB-4655

Project description:Transcription profiling by high throughput sequencing of Arabidopsis mutants that are defective in mitochondrial proteins

2017-02-14 | E-MTAB-4655 | ExpressionAtlas

E-GEOD-34654

Project description:Transcription profiling by high throughput sequencing of Arabidopsis fry1 and xrn single and double mutants

2016-05-06 | E-GEOD-34654 | ExpressionAtlas

Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans

Project description:The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss-of-function mutations of stau-1 significantly suppress phenotypes of let-7 family microRNA mutants, a hypomorphic allele of dicer and a lsy-6 microRNA partial loss-of-function mutant. Furthermore, STAU-1 modulates the activity of lin-14, a target of lin-4 and let-7 family microRNAs, and this modulation is abolished when the 3' untranslated region of lin-14 is removed. Deep sequencing of small RNA cDNA libraries reveals no dramatic change in the levels of microRNAs, or other small RNA populations between wild-type and stau-1 mutants, with the exception of certain endogenous siRNAs in the WAGO pathway. The modulation of microRNA activity by STAU-1 does not seem to be associated with the previously reported enhanced exogenous RNAi (Eri) phenotype of stau-1 mutants, since eri-1 exhibits the opposite effect on microRNA activity. Altogether, our results suggest that STAU-1 negatively modulates microRNA activity downstream of biogenesis, possibly by competing with microRNAs for binding on the 3' untranslated region of target mRNAs

2016-03-16 | GSE79217 | GEO

E-GEOD-51047

Project description:Transcription profiling by high throughput sequencing of maize ra1, ra2, ra3 mutants in developing ear primordia

2019-05-14 | E-GEOD-51047 | ExpressionAtlas

E-MTAB-4050

Project description:Transcription profiling by high throughput sequencing of rice oscerk1 mutants treated with two fungus-secreted substances

2019-01-10 | E-MTAB-4050 | ExpressionAtlas