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Millerozyma farinosa

ABSTRACT: A halotolerant and osmotolerant ascomycete yeast.

PROVIDER: PRJNA12493 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR5223762_subreads.fastq.gz	Fastqsanger.gz

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Millerozyma farinosa strain:SM1

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Millerozyma farinosa CBS 7064

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Successful Treatment of Catheter Related Blood Stream Infection By Millerozyma farinosa with Micafungin: A Case Report.

Project description:Millerozyma farinosa (formerly Pichia farinosa) is halotolerant yeast mainly found in food and ubiquitous in the environment. It was a rare yeast pathogen, but it has recently emerged as a cause of fungemia in immunocompromised patients. Optimal therapy for invasive fungal infection by this pathogen remains unclear. We report a case of catheter related blood stream infection caused by M. farinosa in a 71-year-old patient who recovered successfully after removal of the central venous catheter and treatment with micafungin.

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Draft genome sequence data of multi-stress tolerant yeast <i>Millerozyma farinosa</i> KCTC27753 isolated from nuruk.

Project description:The strain Millerozyma farinosa KCTC27753, isolated from nuruk, is a multi-stress tolerant yeast which grows at 46 °C temperature and pH 3.0. This strain can withstand fermentation inhibitors, such as furfural and phenolic compounds released from biomass. Hence, this strain could be used for bioethanol production. The draft genome sequence of M. farinosa KCTC27753 was analyzed by PacBio RSII. The genome length is 21,255,474 bp and it consists of 17 contigs. The GC content of the genome is 41.1%. The genome analysis identified a total of 10,910 plausible gene-coding regions in this strain.

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Millerozyma farinosa strain:KCTC 27753

Project description:Millerozyma farinosa strain:KCTC 27753 Genome sequencing and assembly

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Project description:An ascomycete yeast

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Insights into the life cycle of yeasts from the CTG clade revealed by the analysis of the Millerozyma (Pichia) farinosa species complex.

Project description:Among ascomycetous yeasts, the CTG clade is so-called because its constituent species translate CTG as serine instead of leucine. Though the biology of certain pathogenic species such as Candida albicans has been much studied, little is known about the life cycles of non-pathogen species of the CTG clade. Taking advantage of the recently obtained sequence of the biotechnological Millerozyma (Pichiasorbitophila) farinosa strain CBS 7064, we used MLST to better define phylogenic relationships between most of the Millerozyma farinosa strains available in public collections. This led to the constitution of four phylogenetic clades diverging from 8% to 15% at the DNA level and possibly constituting a species complex (M. farinosa) and to the proposal of two new species:Millerozyma miso sp. nov. CBS 2004(T) (?=?CLIB 1230(T)) and Candida pseudofarinosa sp. nov.NCYC 386(T)(?=?CLIB 1231(T)). Further analysis showed that M. farinosa isolates exist as haploid and inter-clade hybrids. Despite the sequence divergence between the clades, secondary contacts after reproductive isolation were evidenced, as revealed by both introgression and mitochondria transfer between clades. We also showed that the inter-clade hybrids do sporulate to generate mainly viable vegetative diploid spores that are not the result of meiosis, and very rarely aneuploid spores possibly through the loss of heterozygosity during sporulation. Taken together, these results show that in this part of the CTG clade, non-Mendelian genetic exchanges occur at high rates through hybridization between divergent strains from distinct clades and subsequent massive loss of heterozygosity. This combination of mechanisms could constitute an alternative sexuality leading to an unsuspected biodiversity.

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Kluyveromyces aestuarii

Project description:An ascomycete yeast found in marine habitats

| PRJNA49743 | ENA

Transcriptome data of Hyphopichia burtonii and Hyphopichia pseudoburtonii when exposed to high osmosterss (1M NaCl) condtion at several time points.

Project description:The goal and objectives of this experiment are to find out the transcriptomic changes and differences when the two halotolerant yeast H. burtonii and H. pseudoburtonii isolated from Nuruk were exposed to high salt conditions over time. So the RNA-seq anaylsis was perfomred by setting up each time points (0, 5, 15, 30 min) The sequencing data of RNAs obtained from yeast cells cultured in YPD + 1M NaCl at each time were analyzed using YPD condtions as acontrol

2021-01-31 | GSE130141 | GEO

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