Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: Identification of a B cell signature associated with renal transplant Tolerance in humans

OTHER RELATED OMICS DATASETS IN: E-GEOD-22229

PROVIDER: PRJNA128837 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

E-GEOD-22229

Project description:Identification of a B cell signature associated with renal transplant Tolerance in humans

2025-01-24 | E-GEOD-22229 | ExpressionAtlas

Defining a methylation signature associated with operational tolerance in renal transplant

Project description:Defining a methylation signature associated with operational tolerance in renal transplant

| PRJNA657602 | ENA

Homo sapiens

Project description:GENOMICS TO IDENTIFY HLA IDENTICAL RENAL TRANSPLANT TOLERANCE SIGNATURES

| PRJNA194628 | ENA

E-GEOD-21374

Project description:Expression data from human renal allograft biopsies to investigate renal transplant rejection and failure

2025-01-24 | E-GEOD-21374 | ExpressionAtlas

Homo sapiens

Project description:Identification of a stable gene signature of tolerance to renal allograft by meta-analysis.

| PRJNA213613 | ENA

E-GEOD-106675

Project description:Intragraft molecular pathways associated with tolerance induction in renal transplantation

2025-01-16 | E-GEOD-106675 | ExpressionAtlas

Gene expression profiling in B lymphocytes from transplanted patients

Project description:The achievement of a drug-free operational tolerance for renal transplanted patients is a major goal in organ transplantation. Previous gene expression profiling in peripheral blood mononuclear cells (PBMC) identified genes associated with operational tolerance. The identification of a common pattern of B cell-related genes associated with tolerance encourage us to analyze gene expression in purified B cell from operationally tolerant patients (TOL=10) compared to renal transplanted patients with stable graft function (STA=12) under immunosuppression and also compared to healthy volunteers (HV=10) who have no immunosuppressive treatment and no graft. Microarray analyses exhibited an absence of gene signature associated with tolerance in purified B cell compared to STA or HV. These results suggest that the B cell signatures observed in PBMC may be due to an increase number of total B cells rather than specific B cell characteristics in operationally tolerant patients. This dataset represents gene expression profiling of purified B cells from 10 renal transplanted patients with operational tolerance (TOL), 12 renal transplanted patients with stable graft function under immunosuppression (STA) and 10 healthy volunteers (HV).

2015-08-01 | E-GEOD-39899 | biostudies-arrayexpress

Homo sapiens

Project description:Longitudinal Studies of a B-Cell-Derived Signature of Tolerance in Renal Transplantation

| PRJNA277456 | ENA

Homo sapiens

Project description:Transcriptomic signature of the CD24hiCD38hi transitional B cells associated with an immunoregulatory phenotype in renal transplant recipient.

| PRJNA306767 | ENA

Homo sapiens

Project description:Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance

| PRJNA207105 | ENA