Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ehrlichia ruminantium str. Welgevonden

ABSTRACT: Obligate intracellular pathogen that causes heartwater disease in ruminants

PROVIDER: PRJNA13355 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Ehrlichia ruminantium str. Gardel

Project description:Obligate intracellular pathogen that causes heartwater disease in ruminants

| PRJNA13356 | ENA

Ehrlichia ruminantium str. Welgevonden

Project description:Obligate intracellular pathogen that causes heartwater disease in ruminants

| PRJNA9614 | ENA

Ehrlichia ruminantium

Project description:Obligate intracellular bacterium and causative agent of heartwater

| PRJNA13419 | ENA

Global gene expression profiling of Ehrlichia ruminantium virulent and attenuated strains

Project description:The obligate intracellular bacterium, Ehrlichia ruminantium (ER) is the causal agent of Heartwater, a fatal disease in ruminants. It is transmitted by ticks of the genus Amblyomma. Here, we report the genomic comparative and the global transcriptional profile of 4 strains of ER, Gardel and Senegal, two distant virulent strains with their corresponding attenuated strains. Our results showed a higher metabolic activity in attenuated strains compared to virulent strains, suggesting a better adaptation in vitro of attenuated strains to the host cells. There was a strong modification of membrane protein encoding genes expression for the 4 strains. A major over-expression of map1-related genes was observed for virulent strains, whereas attenuated strains over-expressed genes encoding for hypothetical membrane proteins. This result suggests that in vivo, MAP-1 related proteins could induce non-protective immune responses for virulent strains. For the attenuated strains, the lack of expression of map1-related genes and over-expression of other membrane proteins encoding genes could be important in induction of efficient immune responses.The diminution of expression of many genes in attenuated Senegal was caused by severe mutation. One of them, the gene recO is involved in DNA repair and its mutation could explain the higher proportion of mutated genes in attenuated Senegal, inducing the faster attenuation of Senegal compared to Gardel.

2016-05-01 | GSE55726 | GEO

Rickettsia typhi str. Wilmington

Project description:Obligate intracellular pathogen that causes endemic typhus

| PRJNA10679 | ENA

Anaplasma phagocytophilum str. HZ

Project description:Obligate intracellular pathogen that causes human granulocytic anaplasmosis

| PRJNA336 | ENA

Onion yellows phytoplasma OY-M

Project description:Obligate intracellular pathogen that causes onions yellow disease

| PRJNA9615 | ENA

Rickettsia rickettsii str. Iowa

Project description:Obligate intracellular pathogen that causes Rocky Mountain Spotted Fever

| PRJNA19943 | ENA

Rickettsia conorii str. Malish 7

Project description:Obligate intracellular pathogen that causes Rocky Mountain Spotted Fever

| PRJNA42 | ENA

Rickettsia rickettsii str. 'Sheila Smith'

Project description:Obligate intracellular pathogen that causes Rocky Mountain Spotted Fever

| PRJNA9636 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data