Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Latilactobacillus sakei subsp. sakei 23K

ABSTRACT: Used in the production of fermented meat products

PROVIDER: PRJNA13435 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Latilactobacillus sakei subsp. sakei LS25

Project description:Latilactobacillus sakei subsp. sakei LS25 Genome sequencing and assembly

| PRJNA186903 | ENA

Alternative culture medium design for biomass production of autochthonous meat starter Latilactobacillus sakei sp. sakei ACU-2.

Project description:The autochthonous strain Latilactobacillus sakei sp. sakei ACU-2 was selected as a meat starter culture for dry sausage production. Transferring this strain from laboratory scale to industry requires an increase in biomass production, while lowering process costs. In this study, a combination of techniques was applied in order to optimize the culture medium composition to enhance biomass production of L. sakei ACU-2. One variable at a time experiments, Plackett-Burman design, and mixture design were performed to fulfill the strain nutritional requirements. Eventually, the optimized formulation contained 19.46 g/L yeast extract; 8.28 g/L whey protein concentrate; 2.26 g/L soy peptone; 30 g/L cerelose; 1 g/L Tween 80; 5 g/L sodium acetate; 0.2 g/L magnesium sulfate and 0.05 g/L manganese sulfate. When L. sakei ACU-2 was cultivated in a bioreactor using the alternative medium, an enhancement of 75.5% of biomass production was achieved, in comparison to its growth in the commercial de Man, Rogosa, and Sharpe medium. Furthermore, a reduction of 62-86% of the cost was also attained. These results support a promising large-scale application of the designed medium for high biomass yields of the starter culture at minor costs.

| S-EPMC10063532 | biostudies-literature

Latilactobacillus sakei subsp. sakei strain:CBA3649

Project description:Latilactobacillus sakei subsp. sakei strain:CBA3649 Genome sequencing

| PRJNA1128364 | ENA

Latilactobacillus sakei subsp. sakei strain:FBL10

Project description:Latilactobacillus sakei subsp. sakei strain:FBL10 Genome sequencing and assembly

| PRJNA1014363 | ENA

Latilactobacillus sakei subsp. sakei strain:PastSakei12

Project description:Latilactobacillus sakei subsp. sakei strain:PastSakei12 Genome sequencing

| PRJNA1161856 | ENA

Latilactobacillus sakei Wikim0185 alleviates allergic asthma by inducing tolerogenic dendritic cells through epigenetic rewriting

Project description:Kimchi is a traditional Korean food widely recognized for its probiotic properties and potential health benefits. Several lactic acid bacteria (LAB) from Kimchi exhibit immunomodulatory properties, and their efficacy has been evaluated for various immune-related diseases. However, the mechanisms underlying the immunomodulatory effects of LAB are not yet fully understood. In this study, we demonstrated the immunomodulatory effects of Latilactobacillus sakei Wikim0185, isolated from sweet potato Kimchi, in an ovalbumin (OVA)-induced allergic asthma mouse model by inducing tolerogenic dendritic cells (DCs) and regulatory T cells (Tregs). Bone marrow-derived dendritic cells (BMDCs) and OVA-peptide-stimulated splenocytes isolated from OT-II mice co-cultured with Wikim0185 exhibited increased secretion of the anti-inflammatory cytokine IL-10. Oral administration of Wikim0185 in allergic asthma experimental mice alleviated symptoms, including airway hyperresponsiveness (AHR), leukocyte infiltration, and reduced Th2-type cytokine levels in bronchoalveolar lavage (BAL) fluid. Notably, Wikim0185-treated mice displayed an increased proportion of Foxp3+ Tregs in mediastinal lymph nodes. Additionally, mediastinal lymph node cells restimulated with OVA exhibited decreased secretion of Th2-type cytokines while showing increased IL-10 production. Interestingly, RNA sequencing and chromatin immunoprecipitation (ChIP)-qPCR analysis revealed that Wikim0185 induced tolerogenic DCs through epigenetic histone modifications, increasing active chromatin marks (H3K4me3, H3K9ac, and H3K27ac) on the promoter regions of tolerogenic marker genes (Pdl1, Il10, Socs1, and Socs3). These findings suggest that Wikim0185 modulates immune responses by epigenetically reprogramming DCs, thereby promoting Treg differentiation and suppressing excessive Th2 immune responses in an allergic asthma mouse model.

2025-03-19 | GSE291764 | GEO

Latilactobacillus sakei

Project description:Latilactobacillus sakei Genome sequencing

| PRJNA649110 | ENA

Latilactobacillus sakei

Project description:whole genome sequence of Lactobacillus sakei isolated from various food

| PRJDB12616 | ENA

Latilactobacillus sakei

Project description:Latilactobacillus sakei Genome sequencing and assembly

| PRJNA382621 | ENA

Latilactobacillus sakei

Project description:Latilactobacillus sakei Raw sequence reads