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ABSTRACT:
PROVIDER: PRJNA139787 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:This SuperSeries is composed of the following subset Series: GSE28283: Renal cortex microRNA expression differences between hypertensive and normotensive patients GSE28344: Renal medulla microRNA expression differences between hypertensive and normotensive patients GSE28345: Renal cortex expression differences between hypertensive and normotensive patients GSE28360: Renal medulla expression differences between hypertensive and normotensive patients Refer to individual Series
2011-10-14 | E-GEOD-28260 | biostudies-arrayexpress
Project description:Renal medulla microRNA expression differences between hypertensive and normotensive patients
| PRJNA143181 | ENA
Project description:Renal cortex microRNA expression differences between hypertensive and normotensive patients
| PRJNA143211 | ENA
Project description:Renal medulla expression differences between hypertensive and normotensive patients
| PRJNA143165 | ENA
Project description:Renal cortex expression differences between hypertensive and normotensive patients
| PRJNA143183 | ENA
Project description:Identification of renal medulla genes whose expression differs between male individuals with high blood pressure and normal blood pressure using Affymetrix GeneChip Human Gene 1.0 ST Arrays. The Silesian Renal Tissue Bank, a collection of tissue which aimed to investigate candidate genes in human cardiovascular disease, was used to analyze the gene expression in hypertensive and normotensive patients. Approximately 1 cm3 of tissue from the healthy (unaffected by cancer) pole of the kidney was obtained immediately after surgery and transferred into containers with RNAlater (Ambion) and preserved at 70°C before mRNA extraction, which used a commercially available assay (RNeasy, Qiagen). Medulla and cortex were separated and individual RNA was obtained for each of them. No pooling was performed. After extraction of RNA, cRNA was prepared and arrays performed using Affymetrix GeneChip Human Gene 1.0 ST Arrays performed at the Ramaciotti Gene Function Analysis facility, University of New South Wales in Sydney, Australia.
2011-10-14 | E-GEOD-28360 | biostudies-arrayexpress
Project description:Identification of renal medulla microRNAs whose expression differs between male individuals with high blood pressure and normal blood pressure using Agilent Human miRNA Microarrays (V3, release 12.0). The Silesian Renal Tissue Bank, a collection of tissues which aimed to investigate candidate genes in human cardiovascular disease, was used to analyze the miRNA expression in hypertensive and normotensive patients. Approximately 1 cm3 of tissue from the healthy (unaffected by cancer) pole of the kidney was obtained immediately after surgery and transferred into containers with RNAlater (Ambion) and preserved at 70°C before mRNA extraction, which used a commercially available assay (RNeasy, Qiagen). Medulla and cortex were separated and individual RNA was obtained for each of them. No pooling was performed. After extraction of RNA, cRNA was prepared and arrays performed using Agilent Human miRNA Microarrays (V3, release 12.0) performed at the Ramaciotti Gene Function Analysis facility, University of New South Wales in Sydney, Australia.
2011-10-14 | E-GEOD-28344 | biostudies-arrayexpress
Project description:Identification of renal cortex genes whose expression differs between male individuals with high blood pressure and normal blood pressure using Affymetrix GeneChip Human Gene 1.0 ST Arrays. The Silesian Renal Tissue Bank, a collection of tissue which aimed to investigate candidate genes in human cardiovascular disease, was used to analyze the gene expression in hypertensive and normotensive patients. Approximately 1 cm3 of tissue from the healthy (unaffected by cancer) pole of the kidney was obtained immediately after surgery and transferred into containers with RNAlater (Ambion) and preserved at 70°C before mRNA extraction, which used a commercially available assay (RNeasy, Qiagen). Medulla and cortex were separated and individual RNA was obtained for each of them. No pooling was performed. After extraction of RNA, cRNA was prepared and arrays performed using Affymetrix GeneChip Human Gene 1.0 ST Arrays performed at the Ramaciotti Gene Function Analysis facility, University of New South Wales in Sydney, Australia.
2011-10-14 | E-GEOD-28345 | biostudies-arrayexpress
Project description:Identification of renal cortex microRNAs whose expression differs between male individuals with high blood pressure and normal blood pressure using Agilent Human miRNA Microarrays (V3, release 12.0). The Silesian Renal Tissue Bank, a collection of tissues which aimed to investigate candidate genes in human cardiovascular disease, was used to analyze the miRNA expression in hypertensive and normotensive patients. Approximately 1 cm3 of tissue from the healthy (unaffected by cancer) pole of the kidney was obtained immediately after surgery and transferred into containers with RNAlater (Ambion) and preserved at 70°C before mRNA extraction, which used a commercially available assay (RNeasy, Qiagen). Medulla and cortex were separated and individual RNA was obtained for each of them. No pooling was performed. After extraction of RNA, cRNA was prepared and arrays performed using Agilent Human miRNA Microarrays (V3, release 12.0) performed at the Ramaciotti Gene Function Analysis facility, University of New South Wales in Sydney, Australia.
2011-10-14 | E-GEOD-28283 | biostudies-arrayexpress
Project description:Medulla oblongata is a region of the brain containing multiple blood pressure regulation centers, including the nucleus of the solitary tract (NTS), a pivotal region for regulating the set-point of arterial pressure. Our previous findings suggest that the NTS of male pre-hypertensive rats and spontaneously hypertensive rats (SHRs) exhibits abnormal inflammatory condition compared with that of normotensive Wistar-Kyoto (WKY) rats. Females of SHRs exhibit a lower blood pressure than their male counterpart but the molecular mechanism is not well described. To unveil the gender differences in the central regulation of blood pressure, we investigated the gene expression profile of cytokines and chemokines in the medulla oblongata of female SHRs compared to that of their male counterparts.
2016-10-12 | GSE87746 | GEO