Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

WU-BC 3, 4, and 5 PAM50 Subtypes with Passage and Gene Expression Comparison Between Xenografts and Primary Tumors

ABSTRACT: WU-BC 3, 4, and 5 PAM50 Subtypes with Passage and Gene Expression Comparison Between Xenografts and Primary Tumors

PROVIDER: PRJNA140693 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

WU-BC 3, 4, and 5 PAM50 Subtypes with Passage and Gene Expression Comparison Between Xenografts and Primary Tumors

Project description:Whole genome expression studies were performed on Xenograft panels with multiple passages from 3 different patient tumors. We assessed the global gene expression concordance from passages to passage and from passage to primary tumor when available and performed PAM50 subtype classification. These results were examined within the context of 40 PAM50 prototype experiments.

2012-10-10 | GSE28860 | GEO

cirRNA-seq of the fourth passage xenografts treated with 5-Fu and PBS

Project description:In this study, we established a successive xenograft model to enrich Epstein-Barr virus-associated gastric carcinoma (EBVaGC) cancer stem cells (CSCs) through long-term treatment of EBVaGC cell line SNU719 with 5-Fluorouraci (5-Fu) in mice vivo passage. Simply, NOD/SCID mice injected in the subcutaneous with SNU719 were treated with 5-Fu weekly until xenografts reached 1.5 cm diameter and the mice were euthanizedand single-cell suspensions were obtainedby collagenasedigestion. Then the purified cells were passaged in 5-Fu-treated NOD/SCID mice as above. After four successive generations,we obtained theSNU-4th cells from the fourth passage xenografts treated with 5-Fu. Compared with parental SNU719 cells, SNU-4th cells possessed the stemness characters. Increasing evidence have proved that circular RNA (circRNA) play an important role in maintaining the tumor phenotype. So, we compared circRNAs expression between the fourth passage xenografts treated with 5-Fu and PBS by RNA-sequencing, hoping to find out which circRNAs were involved in the stemness regulation of EBVaGC. we established a highly malignant EBVaGC cell line SNU-4th through long-term treatment of EBVaGC cell line SNU719 with 5-Fluorouraci in vivo passage, then we compared circRNAs expression between the fourth passage xenografts treated with 5-Fu and PBS by RNA-sequencing

2020-02-26 | GSE145894 | GEO

WU Polyomavirus

Project description:WU Polyomavirus Genome sequencing and assembly

| PRJNA663189 | ENA

WU Polyomavirus

Project description:WU Polyomavirus Genome sequencing and assembly

| PRJNA663191 | ENA

Halomonas sp. BC strain:BC

Project description:Halomonas sp. BC strain:BC Genome sequencing

| PRJNA259513 | ENA

cirRNA-seq of the fourth passage xenografts treated with 5-Fu and PBS

Project description:cirRNA-seq of the fourth passage xenografts treated with 5-Fu and PBS

| PRJNA608689 | ENA

Primary effusion lymphoma cell lines BC-1 and BC-3

Project description:Microarray analysis of primary effusion lymphoma cell lines BC-1 and BC-3 Total RNA from BC-1 and BC-3 cell lines was processed for analysis in one replicate on Human Gene 1.0 ST arrays to obtain data on whether genes are expressed and to compare to existing microarray data.

2011-11-16 | E-GEOD-31745 | biostudies-arrayexpress

Differentially expressed miRNAs in xenografts and organoids derived from human cholangiocarcinoma [miRNA]

Project description:We established xenografts and organoids derived from human cholangiocarcinoma. To investigate the signature of cancer stem cells, miRNA expression profiles were analyzed in cholangiocarcinoma xenografts and organoids (passage 7). Microarray analyses were conducted in cholangiocarcioma xenografts and organoids (passage 7).

2016-04-01 | E-GEOD-67209 | biostudies-arrayexpress

Differentially expressed miRNAs in xenografts and organoids derived from human cholangiocarcinoma [miRNA]

2016-04-01 | GSE67209 | GEO

Expression data from patient and primary xenografts esophageal tumour samples

Project description:Microarrays were used to assess differences between 1) human tumours that did and did not engraft, 2) human tumours and their matched primary xenografts, 3) early and late passage primary xenografts and 4) small and large primary xenografts for a series of esophageal patient and primary xenograft tumours

2015-01-11 | GSE58870 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data