Project description:Deep whole genome sequencing of Drosophila melanogaster inbred lines: DGRP-28, DGRP-307, DGRP-399, DGRP-57, DGRP-639, DGRP-712, DGRP-714, DGRP-852 and Virginizer (VGN). The lines were sequenced deeply giving between 54M and 92M reads to achieve a whole genome coverage that ranged between 74X and 125X. The sequencing was used for de novo genotyping.

2025-01-22 | E-MTAB-14209 | biostudies-arrayexpress

Complete de novo assembly of Wolbachia endosymbiont of Drosophila melanogaster using long-read genome sequencing.

Project description:De novo assembly of Wolbachia in Drosophila melanogaster

| PRJEB107252 | ENA

Complete de novo assembly of Wolbachia endosymbiont of contemporary Drosophila simulans using long-read genome sequencing.

Project description:De novo assembly of Wolbachia in Drosophila simulans

| PRJEB107302 | ENA

ChIP-Seq of six Drosophila species with anti-Drosophila melanogaster Twist and anti-Snail antibodies using different library fragment sizes

Project description:The binding patterns of some transcription factors have been shown to diverge substantially between closely related species. Here, we show that the binding pattern of the developmental transcription factor Twist is highly conserved across six Drosophila species, revealing strong functional constraints at developmental enhancers. Conserved binding correlates with sequence motifs for Twist and its partners, permitting the de novo discovery of their cooperative binding. It also includes over 10,000 low-occupancy sites near the detection limit, which tend to mark enhancers of later developmental stages. We predict that conservation, dynamic occupancy, and combinatorial regulation will be generally true for developmental enhancers.

2010-12-07 | E-MTAB-376 | biostudies-arrayexpress

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