Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Lactobacillus psittaci

ABSTRACT: Lactobacillus psittaci overview

PROVIDER: PRJNA189152 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR896450_1.fastq.gz	Fastqsanger.gz
	SRR896450_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

Lactobacillus psittaci DSM 15354

Project description:Lactobacillus psittaci DSM 15354

| PRJNA188921 | ENA

Chlamydophila psittaci negative ocular adnexal marginal zone lymphomas express self polyreactive B cell receptors

Project description:The pathogenesis of Chlamydophila (C.) psittaci negative ocular adnexal extranodal marginal zone lymphomas (OAEMZLs) is poorly understood. OAEMZLs are monoclonal tumors expressing a biased repertoire of mutated surface immunoglobulins. Antigenic activation of the B cell receptor (BCR) may play a role in the pathogenesis of these lymphomas. We have analyzed the reactivity of recombinant OAEMZL immunoglobulins. OAEMZL antibodies reacted with self-human antigens, as demonstrated by enzyme-linked immunosorbent assays, HEp-2 immunofluorescence and human protein microarrays. All the analyzed recombinant antibodies (rAbs) exhibited polyreactivity by comprehensive protein array antibody reactivity and some rAbs also demonstrated rheumatoid factor activity. The identity of several reactive antigens was confirmed by microcapillary reverse-phase HPLC nano-electrospray tandem mass spectrometry. The tested rAbs frequently reacted with shared intracellular and extracellular self-antigens (e.g. galectin-3). Furthermore, these self-antigens induced BCR signaling in B cells expressing cognate surface immunoglobulins derived from OAEMZLs. These findings suggest that interactions between self-antigens and cognate OAEMZL tumor-derived BCRs are functional, inducing intracellular signaling. Overall our findings suggest that self-antigen-induced BCR stimulation may be implicated in the pathogenesis of C. psittaci negative OAEMZLs.

2015-01-30 | GSE65443 | GEO

Chlamydophila psittaci negative ocular adnexal marginal zone lymphomas express self polyreactive B cell receptors

2015-01-30 | E-GEOD-65443 | biostudies-arrayexpress

Chlamydia psittaci

Project description:Chlamydia psittaci Metagenomic assembly

| PRJNA895112 | ENA

Chlamydia psittaci

Project description:Transmission of Chlamydia psittaci

| PRJNA734433 | ENA

Chlamydia psittaci

Project description:Chlamydia psittaci Metagenomic assembly

| PRJNA776714 | ENA