Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Burkholderia oklahomensis

ABSTRACT: Isolated from wounds associated with soil contamination

PROVIDER: PRJNA19545 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR1614082_subreads.fastq.gz	Fastqsanger.gz
	SRR1614083.fastq.gz	Fastqsanger.gz
	SRR1614083_1.fastq.gz	Fastqsanger.gz
	SRR1614083_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Burkholderia oklahomensis C6786

Project description:Isolated from a leg wound

| PRJNA19535 | ENA

Burkholderia oklahomensis EO147 strain:E0147

Project description:Isolated from an ocular ulcer

| PRJNA19537 | ENA

Burkholderia oklahomensis C6786

Project description:Burkholderia oklahomensis C6786 Genome sequencing

| PRJNA238548 | ENA

Burkholderia oklahomensis strain:EO147

Project description:Burkholderia oklahomensis strain:EO147 Genome sequencing

| PRJNA244064 | ENA

Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity.

Project description:Burkholderia oklahomensis EO147 agglutinin (BOA) is a 29 kDa member of the Oscillatoria agardhii agglutinin (OAA) family of lectins. Members of the OAA family recognize high-mannose glycans, and, by binding to the HIV envelope glycoprotein 120 (gp120), block the virus from binding to and entering the host cell, thereby inhibiting infection. OAA-family lectins comprise either one or two homologous domains, with a single domain possessing two glycan binding sites. We solved the structure of BOA in the ligand-free form as well as in complex with four molecules of 3?,6?-mannopentaose, the core unit of the N-linked high-mannose structures found on gp120 in vivo. This is the first structure of a double-domain OAA-family lectin in which all four binding sites are occupied by ligand. The structural details of the BOA-glycan interactions presented here, together with determination of affinity constants and HIV inactivation data, shed further light onto the structure-function relationship in this important class of anti-HIV proteins.

| S-EPMC3745830 | biostudies-literature

Identification of potential therapeutic targets for Burkholderia cenocepacia by comparative transcriptomics

Project description:[1] Transcription profiling of one Burkholderia cenocepacia clinical isolate, J2315, versus a soil isolate, HI2424, in conditions mimicking CF sputum [2] Transcription profiling of Burkholderia cenocepacia isolates J2315 and HI2424 in media mimicking CF sputum or the soil environment

2009-12-01 | GSE15817 | GEO

Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing

Project description:Transcriptional profiling of RNA-seq data from two Burkholderia species grown under conditions mimicking the cystic fibrosis lung and the soil environment

2009-11-21 | GSE19115 | GEO

Comparative transcriptomics of Burkholderia pseudomallei from soil media and infected host

Project description:Burkholderia pseudomallei can adapt to and thrive in a variety of environments, including soil and water, and also can infect different hosts, including humans, leading to the tropical disease melioidosis. Modulation of gene and protein expression is one of this pathogen's adaptive survival mechanisms, which could lead to changes in the bacteria's cell membrane, metabolism, and virulence. To better understand bacterial adaptation and host-pathogen interactions, this study compared the expression profiles of B. pseudomallei from infected mice to B. pseudomallei cultivated in soil extract media. B. pseudomallei in vivo was created by infecting mice through the intraperitoneal route and harvesting the spleens on day 5 post infection. Total RNA was isolated and sequenced from the harvested spleen. Sequence reads were mapped to the B. pseudomallei UKMD286 strain genome sequence.

2022-07-22 | E-MTAB-11200 | biostudies-arrayexpress

Coagulation

Project description:Bacteria isolated from burns human wounds

| PRJEB22846 | ENA

Project description:Soil Cr contamination

| PRJNA888338 | ENA