Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

ABSTRACT: Transcriptomic profiling of Salmonella Typhimurium upon desiccation on stainless steel and subsequent rehydration

PROVIDER: PRJNA202291 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptomic profiling of Salmonella Typhimurium upon desiccation on stainless steel and subsequent rehydration

2013-05-09 | GSE46763 | GEO

Whole genome sequencing of preservative-exposed Salmonella enterica serovar Typhimurium to determine single nucleotide polymorphisms (SNPs) that are selected over evolutionary time

Project description:Antimicrobials have been shown to select for changes in biofilm formation and multidrug susceptibility in common human pathogens. We investigated whether common food preservatives selected for these changes in the food pathogen Salmonella enterica serovar Typhimurium. Bacteria were exposed to four food preservatives in either planktonic cultures or biofilms grown on stainless steel beads. Cultures were passaged into fresh media supplemented with the food preservative every 72 hours. Following approximately 1000 generations of continuous preservative exposure, populations were sequenced to determine the single nucleotide polymorphisms that were selected for over evolutionary time.

2024-06-01 | E-MTAB-13967 | biostudies-arrayexpress

Salmonella enterica serovar Typhimurium 4/74 transcriptomics using strand-specific RNA-seq

Project description:Bacterial transcription networks typically consist of hundreds of transcription factors and thousands of promoters. However, current attempts to map bacterial promoters have failed to report the true complexity of bacterial transcription. The differential RNA-seq (dRNA-seq) approaches only identified a subset of promoters because they involved few growth conditions. Here, we present a simplified approach for global promoter identification in bacteria, based upon the analysis of RNA-seq data from multiple environmental conditions. RNA was extracted from Salmonella enterica serovar Typhimurium (S. Typhimurium) grown in 22 different environmental conditions, which were devised to reflect the pathogenic lifestyle of S. Typhimurium. Individual RNA samples were combined into two pools for sequencing. In just two runs of strand-specific RNA-seq and dRNA-seq of the pooled sample we identified 3701 promoters (Pool sample). In further experiments, we found that individual in vitro conditions stimulate the expression of about 60% of the S. Typhimurium genome, whereas the suite of 22 conditions induced expression of 87% of S. Typhimurium genes. We discovered environmental conditions that induce many genes within Salmonella pathogenicity islands and identified 78 new sRNAs. In S. Typhimurium there is now experimental evidence for 280 sRNAs, and we classified them in terms of location and Hfq-binding.

2013-12-18 | GSE49829 | GEO

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

Project description:Salmonella Typhimurium: Immobilized growth vs. Planktonic growth

| PRJNA146511 | ENA

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

Project description:Salmonella enterica subsp. enterica serovar Typhimurium Genome sequencing

| PRJNA313139 | ENA

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

Project description:Salmonella enterica subsp. enterica serovar Typhimurium str. 474 genome sequencing project

| PRJNA56087 | ENA

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

Project description:Salmonella enterica serovar Typhimurium 4/74 transcriptomics using strand-specific RNA-seq

| PRJNA215033 | ENA

Transcriptomic profiling of Salmonella Typhimurium upon desiccation on stainless steel and subsequent rehydration

Project description:Transcriptional profiles of Salmonella Typhimurium str. ST4/74 air-dried onto stainless steel for 4 h was compared to an early stationary phase (ESP) culture control. Cells that had been air-dried for 4 h were then subsequently rehydrated with water for a 30 min period, after which the transcriptional profile was compared to an ESP control. Carried out using 2 biological replicates for each sample; hybridised in a two-channel hybridization against Salmonella genomic DNA as the comparator/reference.

2013-05-09 | E-GEOD-46763 | biostudies-arrayexpress

Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74

Project description:Intra-macrophage transcriptome of Salmonella enterica serovar Typhimurium 4/74 using strand-specific RNA-seq

| PRJNA257106 | ENA

Salmonella enterica serovar Typhimurium 4/74 transcriptomics using strand-specific RNA-seq

2013-12-18 | E-GEOD-49829 | biostudies-arrayexpress