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Danio rerio

ABSTRACT: Danio rerio Targeted Locus (Loci)

PROVIDER: PRJNA213666 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR946442.fastq.gz	Fastqsanger.gz
	SRR946443.fastq.gz	Fastqsanger.gz
	SRR946444.fastq.gz	Fastqsanger.gz
	SRR946445.fastq.gz	Fastqsanger.gz
	SRR946446.fastq.gz	Fastqsanger.gz

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Danio rerio

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Mechanism suppressing transcription of the globin genes in Danio rerio nonerythroid cells

Project description:In genomes of modern fish and amphibia α- and β- globin genes are grouped at a single locus that may resemble the ancestral one and is syntenic to α-globin locus of modern warm-blooded vertebrates. In Danio rerio, the major locus of α/β globin genes comprises two subclusters, one of them harboring genes expressed in adult and the other – genes expressed in embryonic and larval erythrocytes. The results of our previous study suggested that the adult subcluster of this locus has evolved into α-globin gene domain of vertebrate animals. Here we studied how adult and embryo-larval genes of Danio rerio major globin gene locus are repressed in fibroblasts. The results obtained suggest that that at least some of the globin genes present within the adult subcluster are repressed by Polycomb similarly to human α-globin genes. Furthermore, within two α/β gene pairs repression of α-type and β-type genes appears to be mediated by different mechanisms as increasing the level of histone acetylation can activate transcription of only β-type genes.

2020-07-17 | GSE154562 | GEO

Sequencing of Danio rerio skin for 5 age groups

Project description:Comparison of temporal small RNA gene expression profiles from Danio rerio skin. The smallRNA-seq data comprise 5 age groups at 6, 12, 24, 36 and 42 months. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

2021-10-19 | GSE117820 | GEO

Sequencing of Danio rerio brain for 5 age groups

Project description:Comparison of temporal small RNA gene expression profiles from Danio rerio brain. The smallRNA-seq data comprise 5 age groups at 6, 12, 24, 36 and 42 months. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

2021-10-19 | GSE117807 | GEO

Danio rerio cultivar:Danio rerio

Project description:Danio rerio cultivar:Danio rerio Transcriptome or Gene expression

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Sequencing of Danio rerio liver for 2 age groups

Project description:Comparison of Danio rerio liver for 2 age groups treated with Rotenone. The RNA-seq data comprisess two age groups treated with Rotenone. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)

2021-10-19 | GSE102428 | GEO

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