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Gadus morhua

ABSTRACT: Transcriptome in fast skeletal muscle in Atlantic cod throughout the reproductive cycle

PROVIDER: PRJNA213730 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR955389.fastq.gz	Fastqsanger.gz
	SRR955390.fastq.gz	Fastqsanger.gz
	SRR955391.fastq.gz	Fastqsanger.gz
	SRR955392.fastq.gz	Fastqsanger.gz
	SRR955393.fastq.gz	Fastqsanger.gz

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Project description:Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in these processes. Four Ppar subtypes from Atlantic cod (Gadus morhua) were recently cloned and characterized. However, the downstream regulatory role of Ppars in cod lipid metabolism is presently not well understood or described. Here we study the involvement of Atlantic cod Ppar subtypes in systemic regulation of lipid metabolism using the model agonists WY14,643, GW501516, and tetradecylthioacetic acid, employing a multiple omics approach after an in vivo exposure situation.

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