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Sus scrofa

ABSTRACT: A comprehensive profile of microRNAs in the backfat tissue from castrated and intact full-sib pair male pigs

PROVIDER: PRJNA217840 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR987590.fastq.gz	Fastqsanger.gz
	SRR987600.fastq.gz	Fastqsanger.gz

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Circular RNAs,mRNAs and lncRNAs in backfat associated with porcine castration-related fat deposition

Project description:We firstly compared the expression file of circRNAs, mRNAs and lncRNAs in backfat between the castrated and intact Huainan male pigs to identify the key circRNAs, mRNAs and lncRNAs involved in the genetic basis of castration associated fat deposition.

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Project description:An M307 G/A point mutation of FUT1 gene has been considered as a usful marker to select the piglets that are sensitive(GG/AG genotype) or resistant(AA) to Escherichia coli F18 in foreign pig breeds. However,it is not suitable to Chinese native breeds. Duodenal tissues were collected from 3 full-sib pairs of Sutai pigs (a new hybrid between the Duroc and Taihu breeds) at the age of 28-day differing in adhesion phenotype to find the differential miRNAs that can provide the basis for analyzing the different mechanisms of E.coli F18 resistance between foreign and Chinese native breeds,as well as for breeding for disease resistance in Chinese native breeds in the future. piglets at the age of 28-day sensitive(GG genotype) to Escherichia coli F18 vs resistant(AA) ones.Biological replicates:3 full-sib pairs of Sutai pigs(3 pairs for GG/AA genotype of FUT1 gene).One GG sample (512 piglet) was sequenced twice to verify the result. 2385 piglet and 2383 piglet were a pair of full-sib with AA and GG genotype at M307 positionof FUT1 gene, respectively. Unfortunately, the sequencing of 2385 was a failure and was excluded. 2385 piglet has an AA genotype of the FUT1 gene

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