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Mus musculus strain:B6.129

ABSTRACT: RNA sequencing - peritoneal macrophages congenic B6.129 mice lacking or expressing Prnp

PROVIDER: PRJNA218576 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR986792_1.fastq.gz	Fastqsanger.gz
	SRR986792_2.fastq.gz	Fastqsanger.gz
	SRR986793_1.fastq.gz	Fastqsanger.gz
	SRR986793_2.fastq.gz	Fastqsanger.gz
	SRR986794_1.fastq.gz	Fastqsanger.gz

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Impact of Prnp genetic ablation in the hippocampus transcriptome of congenic B6.129-PrnpZH1/ZH1 or coisogenic C57BL/6-PrnpZH3/ZH3 mice

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Impact of Prnp genetic ablation in the hippocampus transcriptome of congenic B6.129-PrnpZH1/ZH1 or coisogenic C57BL/6-PrnpZH3/ZH3 mice

Project description:To study the effect of Prnp genetic ablation on different aspects of RNA metabolism, we performed RNA sequencing of the hippocampus of wild-type C57BL/6J, congenic B6.129-PrnpZH1/ZH1 and coisogenic C57BL/6J-PrnpZH3/ZH3 mice. We analyzed differential gene expression, exon usage and RNA editing. RNA sequencing on hippocampus of wild-type C57BL/6 mice, congenic B6.129-PrnpZH1/ZH1 and coisogenic C57BL/6-PrnpZH3/ZH3 mice (3 month-old males, n=4 per genotype).

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