Homo sapiens
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA219425 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR988499_1.fastq.gz | Fastqsanger.gz | |||
| SRR988499_2.fastq.gz | Fastqsanger.gz | |||
| SRR988500_1.fastq.gz | Fastqsanger.gz | |||
| SRR988500_2.fastq.gz | Fastqsanger.gz | |||
| SRR988501_1.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 5 of 24 |
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Project description:Using genome-wide expression profiles from persons either experimentally challenged with malaria-infected mosquitoes or naturally-infected with Plasmodium falciparum malaria, we present details of the transcriptional changes that occur with infection and that are either commonly shared between subjects with pre-symptomatic and clinically apparent malaria or that distinguish these two groups. Our findings confirm and extend aspects of the earliest responses to malaria infection at the molecular level and which may be informative in elucidating how innate and adaptive immune responses may be modulated in different stages of infection. Experiment Overall Design: Compared samples from patients with naturally acquired malaria infection to those from volunteers in a challenge model vaccine trial.
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Project description:To study pathways associated with ferroptosis sensitivity
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