Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus strain:C57BL/6J

ABSTRACT: Identification of genes in Smad3 WT and KO mice kidney

PROVIDER: PRJNA223210 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1205140_1.fastq.gz	Fastqsanger.gz
	SRR1205140_2.fastq.gz	Fastqsanger.gz
	SRR1205150_1.fastq.gz	Fastqsanger.gz
	SRR1205150_2.fastq.gz	Fastqsanger.gz
	SRR1205141_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Mus musculus strain:C57BL/6J

Project description:Investigation of differentially expressed genes in CKD model mice kidney

| PRJDB6536 | ENA

Identification of genes associated with TGF-beta/Smad3-mediated renal inflammation and fibrosis by RNA sequencing

Project description:In this study, we employed high-throughput RNA sequencing (RNA-Seq) to identify the Smad3-dependent lncRNAs related to renal inflammation and fibrosis in Smad3 knockout (KO) mouse models of unilateral ureteral obstructive nephropathy (UUO) and immunologically-induced anti-glomerular basement membrane glomerulonephritis (anti-GBM GN). 12 kidney tissue samples of Smad3 KO/WT mice from normal control, UUO at day 5 or anti-GBM GN at day 10 models (n=2 in each group) for whole transcriptome RNA-sequencing.

2014-03-26 | E-GEOD-55808 | biostudies-arrayexpress

Mus musculus strain:C57BL/6J

Project description:RNA-seq analysis of duodenal muscularis externa derived from IP6K2-KO mice and WT counterparts

| PRJDB14237 | ENA

Mus musculus musculus breed:C57BL/6J

Project description:Circadian timecourse analysis of WT mice and mice with liver specific Jarid1a KO under regular or High Fat Diet

| PRJNA322074 | ENA

Mus musculus strain:C57BL/6J

Project description:mRNA sequencing for gene expression in kidney of KO mouse

| PRJNA984810 | ENA

Characterizing phenotypic data of Peromyscus leucopus compared to C57BL/6J Mus musculus and diversity outbred (DO) Mus musculus.

Project description:Translational research is commonly performed in the C57B6/J mouse strain, chosen for its genetic homogeneity and phenotypic uniformity. Here, we evaluate the suitability of the white-footed deer mouse (Peromyscus leucopus) as a model organism for aging research, offering a comparative analysis against C57B6/J and diversity outbred (DO) Mus musculus strains. Our study includes comparisons of body composition, skeletal muscle function, and cardiovascular parameters, shedding light on potential applications and limitations of P. leucopus in aging studies. Notably, P. leucopus exhibits distinct body composition characteristics, emphasizing reduced muscle force exertion and a unique metabolism, particularly in fat mass. Cardiovascular assessments showed changes in arterial stiffness, challenging conventional assumptions and highlighting the need for a nuanced interpretation of aging-related phenotypes. Our study also highlights inherent challenges associated with maintaining and phenotyping P. leucopus cohorts. Behavioral considerations, including anxiety-induced responses during handling and phenotyping assessment, pose obstacles in acquiring meaningful data. Moreover, the unique anatomy of P. leucopus necessitates careful adaptation of protocols designed for Mus musculus. While showcasing potential benefits, further extensive analyses across broader age ranges and larger cohorts are necessary to establish the reliability of P. leucopus as a robust and translatable model for aging studies.

| S-EPMC11335981 | biostudies-literature

Mus musculus

Project description:Nas1 KO mice versus WT mice total kidney comparison

| PRJNA99089 | ENA

Project description: Not available

| S-EPMC6924556 | biostudies-literature

Mus musculus strain:C57BL/6J

Project description:Transcriptome analysis of skeletal muscle in large Maf KO mice

| PRJDB13446 | ENA

Mus musculus strain:C57BL/6J

Project description:RNA-seq analysis of fibrotic livers from Treg specific Amphiregulin KO mice.

| PRJDB10114 | ENA