Project description:To investigate how LATS2 affect Wnt target genes expression, we performed gene expression profiling and comparison in control, LATS2 and LATS2N (1-625, kinase domain deletion) overexpression in human colorectal cancer SW480 cells. In SW480 cell line, the stable expression of LATS2 or LATS2N was generated. Total RNA was extracted from these 2 samples and control cell line