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Gut metagenome

ABSTRACT: Effects of prebiotic, probiotic and synbiotic on caecal microbial diversity of laying hens

PROVIDER: PRJNA235148 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1139620_1.fastq.gz	Fastqsanger.gz
	SRR1139620_2.fastq.gz	Fastqsanger.gz
	SRR1138341_1.fastq.gz	Fastqsanger.gz
	SRR1138341_2.fastq.gz	Fastqsanger.gz
	SRR1139731_1.fastq.gz	Fastqsanger.gz

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Synbiotic-Derived Metabolites Alleviate Stress-Induced Depression by Regulating Lymphocyte Activation through the Aryl Hydrocarbon Receptor

Project description:Synbiotics are a combination of probiotics and prebiotics which can alter the composition of the gastrointestinal tract evoking beneficial effects throughout the body through the production of a battery of bioactive metabolites. In this study, a synbiotic was used to reduce the behavioral and biochemical symptoms of depression and this nanostring panel was used to decipher where along the gut-brain-axis the synbiotic-derived metabolites were invoking their beneficial effects on the immune system. The synbitoic was composed of two probiotic bacteria (Lactobacillus fermentum ATCC 793 and Bifidobacteria longum ATCC 15707 and a grape -derived prebiotic composed of grape seed polyphenol extract, resveratrol and a concord grape extract. Male mice (C57BL/6) were pretreatment with either nothing (control), BDPP, probiotic or synbiotic and underwent 28 days of chronic unpredicitable stress. After 28 days, animals' behavior reflected an increase in depressive- and anxiety-like behavior, rescued specifically by the synbiotic. This nanostring multiplex analysis reveals both tissue- and treatment-specific effects on immune modulators.

2020-11-03 | GSE148579 | GEO

chicken gut metagenome

Project description:Caecal microbiome metagenome of laying hens

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Project description:Caecal microorganisms of laying hens

| PRJNA769552 | ENA

Laying hens 16S gut sequencing

Project description:16S rRNA metabarcoding sequencing of caecal laying hens content.

| PRJEB62837 | ENA

Project description:Microbial diversity of laying hens

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Project description:Microbial diversity on laying hens

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Project description:cecal microbial diversity of laying hens

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gut metagenome

Project description:Gut metagenome of laying hens

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Targeting the gut-lung axis by synbiotic feeding to infants in a randomized controlled trial

Project description:<p>Synbiotics may modulate gut microbiota and prevent infections. In a randomized controlled trial (NCT01625273) infants weaned from breast milk were fed formula with prebiotics (fructo- and galactooligosaccharides) or the same prebiotic formula with <em>Lactobacillus paracasei ssp. paracasei</em> strain F19 (synbiotics) from 1 until 6 months of age. The objective was to examine synbiotic effects on gut microbiota maturation. Fecal samples collected at ages 1, 4, 6 and 12 months (324 samples for microbial and 197 samples for metabolic characterization) were analyzed. We demonstrate enrichment of Bifidobacterium and increases in antimicrobial metabolites derived from microbial fermentation of phenylalanine and pectins in the synbiotic group. The gut microbiota of infants with lower respiratory tract infections (LRTI) were depleted of Lactobacillales but enriched in Klebsiella species and associated antimicrobial resistance genes. These compositional and functional changes of the gut microbiota may be linked to the previously reported reduction of LRTI in the synbiotic group.</p>

2022-11-24 | MTBLS2438 | MetaboLights

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