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Mus musculus

ABSTRACT: Genome-wide Profiling of SRC-2 (NCOA2) binding in mouse prostate [ChIP-Seq]

OTHER RELATED OMICS DATASETS IN: E-GEOD-54678

PROVIDER: PRJNA237587 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1164894.fastq.gz	Fastqsanger.gz
	SRR1164895.fastq.gz	Fastqsanger.gz

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Genome-wide Profiling of SRC-2 (NCOA2) binding in mouse prostate [ChIP-Seq]

Project description:Using genetically engineered mice, overexpressing SRC-2, specifically in the prostate epithelium of PTEN heterozygous mice accelerates PTEN mutation induce tumor progression and develops a metastasis-prone cancer. Here we used ChIP-Seq analysis to identify genome-wide SRC-2 binding sites in mouse prostate. Examination of genome-wide SRC-2 binding in mouse prostate by ChIP-seq analysis. Samples were collected from pooled dorsal-lateral prostates of 7 months old-PTEN flox/+; Rosa26-SRC-2 OE/+ mice. Flash frozen tissues were then sent to Active Motif, Inc. for chromatin extraction and followed by immunoprecipitation using anti-SRC-2 antibody (A300-346A, Bethyl Lab., Inc.).

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