Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Corynebacterium jeikeium

ABSTRACT: Corynebacterium jeikeium Genome sequencing and assembly

PROVIDER: PRJNA238244 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR1535010_1.fastq.gz	Fastqsanger.gz
	SRR1535010_2.fastq.gz	Fastqsanger.gz
	SRR1535011_1.fastq.gz	Fastqsanger.gz
	SRR1535011_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

Corynebacterium jeikeium

Project description:Whole genome sequencing of Corynebacterium jeikeium, an opportunistic pathogen

| PRJDB2029 | ENA

Corynebacterium jeikeium strain:DSM 7171

Project description:Corynebacterium jeikeium DSM 7171 Genome sequencing and assembly

| PRJNA532605 | ENA

Draft genome sequence of Corynebacterium jeikeium BVI

Project description:Draft genome sequence of Corynebacterium jeikeium BVI

| PRJEB16021 | ENA

Corynebacterium jeikeium (525262)

Project description:Co-culture confrontation assays of Corynebacterium jeikeium vs. multi-drug resistance organisms. transcriptome

| PRJNA294781 | ENA

Inducible macrolide resistance in Corynebacterium jeikeium.

Project description:Corynebacterium jeikeium is an opportunistic pathogen primarily of immunocompromised (neutropenic) patients. Broad-spectrum resistance to antimicrobial agents is a common feature of C. jeikeium clinical isolates. We studied the profiles of susceptibility of 20 clinical strains of C. jeikeium to a range of antimicrobial agents. The strains were separated into two groups depending on the susceptibility to erythromycin (ERY), with one group (17 strains) representing resistant organisms (MIC > 128 microg/ml) and the second group (3 strains) representing susceptible organisms (MIC < or = 0.25 microg/ml). The ERY resistance crossed to other members of the macrolide-lincosamide-streptogramin B (MLSb) group. Furthermore, this resistance was inducible with MLSb agents but not non-MLSb agents. Expression of ERY resistance was linked to the presence of an allele of the class X erm genes, erm(X)cj, with >93% identity to other erm genes of this class. Our evidence indicates that erm(X)cj is integrated within the chromosome, which contrasts with previous reports for the plasmid-associated erm(X) genes found in C. diphtheriae and C. xerosis. In 40% of C. jeikeium strains, erm(X)cj is present within the transposon, Tn5432. However, in the remaining strains, the components of Tn5432 (i.e., the erm and transposase genes) have separated within the chromosome. The rearrangement of Tn5432 leads to the possibility that the other drug resistance genes have become included in a new composite transposon bound by the IS1249 elements.

| S-EPMC90589 | biostudies-literature

Corynebacterium

Project description:Corynebacterium Genome sequencing and assembly

| PRJNA978579 | ENA

Corynebacterium

Project description:Corynebacterium Genome sequencing and assembly

| PRJNA312301 | ENA

Corynebacterium

Project description:Corynebacterium Genome sequencing and assembly

| PRJNA393261 | ENA

Corynebacterium

Project description:Corynebacterium Genome sequencing and assembly