Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Penicillium chrysogenum strain:P2niaD18

ABSTRACT: Penicillium chrysogenum P2niaD18 Complete genome sequencing

PROVIDER: PRJNA246057 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Penicillium chrysogenum 4088766

Project description:Penicillium chrysogenum 4088766 Genome sequencing

| PRJNA210202 | ENA

Penicillium chrysogenum

Project description:Penicillium chrysogenum mRNA-seq

| PRJNA353579 | ENA

Penicillium chrysogenum strain:PC0814C

Project description:Penicillium chrysogenum UCB strain PC0814C Genome sequencing

| PRJNA243542 | ENA

Penicillium chrysogenum NCPC10086

Project description:Penicillium chrysogenum NCPC10086 Genome sequencing and assembly

| PRJNA190642 | ENA

Penicillium chrysogenum strain:AS25

Project description:Penicillium chrysogenum AS25 Genome sequencing of an ascosporeisolate

| PRJNA253639 | ENA

Penicillium chrysogenum strain:BIONCL16

Project description:Penicillium chrysogenum strain:BIONCL16 Genome sequencing and assembly

| PRJNA786119 | ENA

Time-course gene expression data from deletion strains of Penicillium chrysogenum

Project description:The recent discovery of a velvet complex containing several regulators of secondary metabolism in the model fungus Aspergillus nidulans raises the question whether similar type complexes direct fungal development in genera other than Aspergillus. Penicillium chrysogenum is the industrial producer of the antibiotic penicillin, whose biosynthetic regulation is barely understood. Here we provide a functional analysis of two major homologues of the velvet complex in P. chrysogenum, that we have named PcvelA and PclaeA. Data from array analysis using a ?PcvelA deletion strain indicate a significant role of PcvelA on the expression of biosynthesis and developmental genes, including PclaeA. Northern hybridization and HPLC quantifications of penicillin titres clearly show that both PcvelA and PclaeA play a major role in penicillin biosynthesis. Both regulators are further involved in different and distinct developmental processes. While PcvelA deletion leads to light independent conidial formation, dichotomous branching of hyphae and pellet formation in shaking cultures, a ?PclaeA strain shows a severe impairment in conidiophore formation in both the light and dark. Bimolecular fluorescence complementation assays finally provide evidence for a velvet-like complex in Penicillium chrysogenum, with structurally conserved components that have distinct developmental roles, illustrating the functional plasticity of these regulators within filamentous ascomycetes. Transcriptomes of PcvelA- and PclaeA- deletion mutants were compared with expression data from recipient strain deltaPcku70 and reference strain P2niaD18 as a control

2010-06-17 | E-GEOD-18585 | biostudies-arrayexpress

Penicillium chrysogenum strain:P2niaD18

Project description:Small RNA sequencing of Penicillium chrysogenum P2niaD18

| PRJNA270038 | ENA

Penicillium chrysogenum strain:delta-ku70FRT2

Project description:Small RNA sequencing of Penicillium chrysogenum

| PRJNA270047 | ENA

Penicillium chrysogenum strain:ITEM 4680

Project description:Penicillium chrysogenum ITEM 4680 Minimal Draft genome sequencing

| PRJNA1080926 | ENA