Project description:In our present study, we found that lncRNA-hPVT1 could promote HCC cell proliferation. We want to know what were the target genes of lncRNA-hPVT1. So we constructed the hPVT1-overexpressed SMMC-771 cells and observed the mRNA profile in hPVT1-overexpressed and control SMMC-771 cells. lncRNA-hPVT1 induced transcriptional changes in SMMC-7721. Two-condition experiment, control (LV-Control) vs lncRNA-hPVT1 expression (LV-hPVT1 Clone2 ). Each has 3 biological repeats.
Project description:lncRNA-ATB induced transcriptional changes in SMMC-7721 Two-condition experiment, control (pcDNA3.1) vs lncRNA-ATB expression (pcDNA3.1-ATB). Each has 3 biological repeats.
Project description:Transcriptional profiling of SMMC-7721 cells comparing control untreated with sub-lethal heat treated cells (50°C for 10 min). Differentially expressed lncRNA and mRNA were measured with an Agilent Human lncRNA+mRNA Array V4.0 (4 × 180 K format) containing 41,000 lncRNAs and 34,000 mRNAs. Goal was to determine the effects of sub-lethal heat treatment on global hepatoma carcinoma cells gene expression.
Project description:Sulfatide significantly promoted hepatocellular carcinoma cells survival, proliferation and angiogenesis. To understand the molecular mechanisms of sulfatide, the transcriptional profiles of lncRNAs in human hepatocellular carcinoma cells SMMC-7721 was investigated with ArrayStar lncRNA microarray with sulfatide treatment. Galactose-cerebroside treatment served as the control.
