Project description:Inflammation is a key component of pathological angiogenesis. Here we induce cornea neovascularisation using sutures placed into the cornea, and sutures are removed to induce a regression phase. We used whole transcriptome microarray to monitor gene expression profies of several genes
Project description:The underlying mechanism for CCO is poorly understood We sought to obtain key players and a potential pathway in disease causation through comparative transcriptome (via RNA-Seq) analyses between cornea with CCO from patient with Fanconi anemia and age-matched normal donor cornea
