Rattus norvegicus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA255367 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Gene expression profiling of ovaries collected from rat treated with pregnant mare serum gonadotropins (PMSG) and without PMSG
| PRJNA283381 | ENA
Project description:Gene expression in rat ovaries treated with DHT
2016-04-07 | E-GEOD-59456 | ExpressionAtlas
Project description:Expression data from neonatal rat ovaries following LPS exposure
| PRJNA200339 | ENA
Project description:Gene expression data from corticosteroid-treated neonatal rat cardiomyocytes
| PRJNA111005 | ENA
Project description:A series of two color gene expression profiles obtained using Agilent 44K expression microarrays was used to examine sex-dependent and growth hormone-dependent differences in gene expression in rat liver. This series is comprised of pools of RNA prepared from untreated male and female rat liver, hypophysectomized (‘Hypox’) male and female rat liver, and from livers of Hypox male rats treated with either a single injection of growth hormone and then killed 30, 60, or 90 min later, or from livers of Hypox male rats treated with two growth hormone injections spaced 3 or 4 hr apart and killed 30 min after the second injection. The pools were paired to generate the following 6 direct microarray comparisons: 1) untreated male liver vs. untreated female liver; 2) Hypox male liver vs. untreated male liver; 3) Hypox female liver vs. untreated female liver; 4) Hypox male liver vs. Hypox female liver; 5) Hypox male liver + 1 growth hormone injection vs. Hypox male liver; and 6) Hypox male liver + 2 growth hormone injections vs. Hypox male liver. A comparison of untreated male liver and untreated female liver liver gene expression profiles showed that of the genes that showed significant expression differences in at least one of the 6 data sets, 25% were sex-specific. Moreover, sex specificity was lost for 88% of the male-specific genes and 94% of the female-specific genes following hypophysectomy. 25-31% of the sex-specific genes whose expression is altered by hypophysectomy responded to short-term growth hormone treatment in hypox male liver. 18-19% of the sex-specific genes whose expression decreased following hypophysectomy were up-regulated after either one or two growth hormone injections. Finally, growth hormone suppressed 24-36% of the sex-specific genes whose expression was up-regulated following hypophysectomy, indicating that growth hormone acts via both positive and negative regulatory mechanisms to establish and maintain the sex specificity of liver gene expression. For full details, see V. Wauthier and D.J. Waxman, Molecular Endocrinology (2008)
2008-05-24 | GSE11529 | GEO
Project description:Gene expression in follicle-stimulating hormone-treated rat Sertoli cells
| PRJNA85229 | ENA
Project description:Gene expression analysis of rat livers treated with pharmaceutical development compounds
| PRJNA118823 | ENA
Project description:Gene expression profiles in liver of F344 rat treated with chemical
| PRJNA195581 | ENA
Project description:Mice under chronic dihydrotestosterone (DHT) exposion represented reproductive and metabolic disorders, which were based on the dysfunction of ovaries and fat tissues. We used microarrays to detail the global programme of gene expression and identified distinct difference in ovaries and gonadal fat pads between DHT-treated mice and control.
2021-04-04 | GSE171431 | GEO
Project description:Gene expression of 7 day combinatorial yohimbine and imipramine treated rat hippocampi
| PRJNA260710 | ENA